Microfluidic device for the separation of blood plasma from capillary samples

Giulia Deiana; Alvaro J. Conde; Conni McCarthy; James Dear; Stewart Smith; Maïwenn Kersaudy-Kerhoas

Microfluidic device for the separation of blood plasma from capillary samples

Giulia Deiana, Alvaro J. Conde, Conni McCarthy, James Dear, Stewart Smith, Maïwenn Kersaudy-Kerhoas^*

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

In this paper, we report a cost-effective, disposable microfluidic microfiltration device for the fast separation of capillary volumes of undiluted whole blood. The proposed device is operated without power or specialist equipment, requiring only a commercial metered device (Minivette^®, Sarstedt) used for the collection of blood from a finger prick to actuate the blood flow in a dead-end filtration setup. The device can extract 27.7 ± 6 μL of 100% pure plasma from 100 μL of undiluted whole blood in three minutes.

Original language	English
Title of host publication	23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences 2019
Publisher	Chemical and Biological Microsystems Society
Pages	764-766
Number of pages	3
ISBN (Electronic)	9781733419000
Publication status	Published - 2019
Event	23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences 2019 - Basel, Switzerland Duration: 27 Oct 2019 → 31 Oct 2019

Conference

Conference	23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences 2019
Abbreviated title	MicroTAS 2019
Country/Territory	Switzerland
City	Basel
Period	27/10/19 → 31/10/19

Keywords

Blood plasma separation
Microfluidics
Point-of-care testing
Sample preparation

ASJC Scopus subject areas

Bioengineering
Chemical Engineering (miscellaneous)

Cite this

@inproceedings{c8d19a14f22e406081958dfc35dd602a,

title = "Microfluidic device for the separation of blood plasma from capillary samples",

abstract = "In this paper, we report a cost-effective, disposable microfluidic microfiltration device for the fast separation of capillary volumes of undiluted whole blood. The proposed device is operated without power or specialist equipment, requiring only a commercial metered device (Minivette{\textregistered}, Sarstedt) used for the collection of blood from a finger prick to actuate the blood flow in a dead-end filtration setup. The device can extract 27.7 ± 6 μL of 100\% pure plasma from 100 μL of undiluted whole blood in three minutes.",

keywords = "Blood plasma separation, Microfluidics, Point-of-care testing, Sample preparation",

author = "Giulia Deiana and Conde, \{Alvaro J.\} and Conni McCarthy and James Dear and Stewart Smith and Ma{\"i}wenn Kersaudy-Kerhoas",

note = "Funding Information: This project was funded by the Engineering and Physical Sciences Research Council (EPSRC) through the EPSRC Centre for Doctoral Training in Intelligent Sensing and Measurement (EP/L016753/1). MKK acknowledges EPSRC EP/R00398X/1. Publisher Copyright: {\textcopyright} 2019 CBMS-0001. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.; 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences 2019, MicroTAS 2019 ; Conference date: 27-10-2019 Through 31-10-2019",

year = "2019",

language = "English",

pages = "764--766",

booktitle = "23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences 2019",

publisher = "Chemical and Biological Microsystems Society",

}

Deiana, G, Conde, AJ, McCarthy, C, Dear, J, Smith, S & Kersaudy-Kerhoas, M 2019, Microfluidic device for the separation of blood plasma from capillary samples. in 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences 2019. Chemical and Biological Microsystems Society, pp. 764-766, 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences 2019, Basel, Switzerland, 27/10/19.

Microfluidic device for the separation of blood plasma from capillary samples. / Deiana, Giulia; Conde, Alvaro J.; McCarthy, Conni et al.
23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences 2019. Chemical and Biological Microsystems Society, 2019. p. 764-766.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - Microfluidic device for the separation of blood plasma from capillary samples

AU - Deiana, Giulia

AU - Conde, Alvaro J.

AU - McCarthy, Conni

AU - Dear, James

AU - Smith, Stewart

AU - Kersaudy-Kerhoas, Maïwenn

N1 - Funding Information: This project was funded by the Engineering and Physical Sciences Research Council (EPSRC) through the EPSRC Centre for Doctoral Training in Intelligent Sensing and Measurement (EP/L016753/1). MKK acknowledges EPSRC EP/R00398X/1. Publisher Copyright: © 2019 CBMS-0001. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.

PY - 2019

Y1 - 2019

N2 - In this paper, we report a cost-effective, disposable microfluidic microfiltration device for the fast separation of capillary volumes of undiluted whole blood. The proposed device is operated without power or specialist equipment, requiring only a commercial metered device (Minivette®, Sarstedt) used for the collection of blood from a finger prick to actuate the blood flow in a dead-end filtration setup. The device can extract 27.7 ± 6 μL of 100% pure plasma from 100 μL of undiluted whole blood in three minutes.

AB - In this paper, we report a cost-effective, disposable microfluidic microfiltration device for the fast separation of capillary volumes of undiluted whole blood. The proposed device is operated without power or specialist equipment, requiring only a commercial metered device (Minivette®, Sarstedt) used for the collection of blood from a finger prick to actuate the blood flow in a dead-end filtration setup. The device can extract 27.7 ± 6 μL of 100% pure plasma from 100 μL of undiluted whole blood in three minutes.

KW - Blood plasma separation

KW - Microfluidics

KW - Point-of-care testing

KW - Sample preparation

UR - https://www.scopus.com/pages/publications/85094952819

M3 - Conference contribution

AN - SCOPUS:85094952819

SP - 764

EP - 766

BT - 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences 2019

PB - Chemical and Biological Microsystems Society

T2 - 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences 2019

Y2 - 27 October 2019 through 31 October 2019

ER -

Microfluidic device for the separation of blood plasma from capillary samples

Abstract

Conference

Keywords

ASJC Scopus subject areas

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