Contrary to the accepted convention, this work shows that Minisci-type C–H alkylation does not require any metal, photocatalyst, light, or prefunctionalization of the readily available and inexpensive carboxylic acids to proceed well under mild conditions. These mild conditions can be utilized for late-stage alkylations of complex molecules, including pharmaceutical compounds and light-sensitive compounds which degrade under photocatalytic conditions.
|Number of pages||5|
|Early online date||24 Oct 2018|
|Publication status||Published - 2 Nov 2018|
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- School of Engineering & Physical Sciences - Associate Professor
- School of Engineering & Physical Sciences, Institute of Chemical Sciences - Associate Professor
Person: Academic (Research & Teaching)