In this paper, new experimental data on the solubility of gaseous ethane in water are reported in the 274.26-343.08 K temperature range for pressures up to 4.952 MPa. A static-analytic apparatus, taking advantage of a pneumatic capillary sampler, is used for fluid sampling. The Valderrama modification of the Patel-Teja equation of state, combined with non-density-dependent mixing rules, is used for modeling the vapor-liquid equilibrium. The new solubility data generated in this work are used for tuning of the binary interaction parameters between ethane and water. Then, these data are compared with some literature data and the results of the thermodynamic model. To further evaluate the performance of the model, a comparison is made between the predicted water content data and some experimental data in the literature. These comparisons show the reliability of the techniques and model presented in this work.