Is there a role of epigenetics in gut microbiome and neurological disorders?

Jibran Sualeh Muhammad*, Ruqaiyyah Siddiqui, Naveed Ahmed Khan*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Cross-talk between gut microbiota and the nervous system in the pathophysiology of neurological diseases has become a recent focus of interest. The underlying mechanisms are complex, and we suggest that they might involve gut bacterial metabolite-induced epigenetic modulations of neurodegenerative disorders. Advances in epigenetic techniques could provide the key to understanding the epigenetics of the gut–brain axis.
Original languageEnglish
Pages (from-to)778-780
Number of pages3
JournalAPMIS
Volume130
Issue number12
Early online date25 Nov 2022
DOIs
Publication statusPublished - Dec 2022

Keywords

  • epigenetics
  • Gut microbiota
  • gut–brain axis
  • neurodegenerative disorders

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Immunology and Allergy
  • Microbiology (medical)

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