Iron(II)-mediated fragmentation of unsaturated hydroperoxy acetals: A rapid synthetic route to 13-membered macrolides

K. J. McCullough; Y. Motomura; A. Masuyama; M. Nojima

Iron(II)-mediated fragmentation of unsaturated hydroperoxy acetals: A rapid synthetic route to 13-membered macrolides

K. J. McCullough
, Y. Motomura
, A. Masuyama
, M. Nojima

School of Engineering & Physical Sciences

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Treatment of (1-hydroperoxy)cyclohexyloxyethyl acrylate with either iron(II) sulfate or iron(II) sulfate/copper(II) chloride affords novel 13-membered macrolides via tandem radical scission-cyclisation reactions.

Original language	English
Pages (from-to)	1173-1174
Number of pages	2
Journal	Chemical Communications
Issue number	11
Publication status	Published - 7 Jun 1998

Cite this

@article{5802db045cea4a06834b11773555a208,

title = "Iron(II)-mediated fragmentation of unsaturated hydroperoxy acetals: A rapid synthetic route to 13-membered macrolides",

abstract = "Treatment of (1-hydroperoxy)cyclohexyloxyethyl acrylate with either iron(II) sulfate or iron(II) sulfate/copper(II) chloride affords novel 13-membered macrolides via tandem radical scission-cyclisation reactions.",

author = "McCullough, \{K. J.\} and Y. Motomura and A. Masuyama and M. Nojima",

year = "1998",

month = jun,

day = "7",

language = "English",

pages = "1173--1174",

journal = "Chemical Communications",

issn = "1364-548X",

publisher = "Royal Society of Chemistry",

number = "11",

}

TY - JOUR

T1 - Iron(II)-mediated fragmentation of unsaturated hydroperoxy acetals

T2 - A rapid synthetic route to 13-membered macrolides

AU - McCullough, K. J.

AU - Motomura, Y.

AU - Masuyama, A.

AU - Nojima, M.

PY - 1998/6/7

Y1 - 1998/6/7

N2 - Treatment of (1-hydroperoxy)cyclohexyloxyethyl acrylate with either iron(II) sulfate or iron(II) sulfate/copper(II) chloride affords novel 13-membered macrolides via tandem radical scission-cyclisation reactions.

AB - Treatment of (1-hydroperoxy)cyclohexyloxyethyl acrylate with either iron(II) sulfate or iron(II) sulfate/copper(II) chloride affords novel 13-membered macrolides via tandem radical scission-cyclisation reactions.

UR - https://www.scopus.com/pages/publications/0032493164

M3 - Article

SN - 1364-548X

SP - 1173

EP - 1174

JO - Chemical Communications

JF - Chemical Communications

IS - 11

ER -

Iron(II)-mediated fragmentation of unsaturated hydroperoxy acetals: A rapid synthetic route to 13-membered macrolides

Abstract

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