Iron(II)-mediated fragmentation of unsaturated hydroperoxy acetals: A rapid synthetic route to 13-membered macrolides

K. J. McCullough, Y. Motomura, A. Masuyama, M. Nojima

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Treatment of (1-hydroperoxy)cyclohexyloxyethyl acrylate with either iron(II) sulfate or iron(II) sulfate/copper(II) chloride affords novel 13-membered macrolides via tandem radical scission-cyclisation reactions.

Original languageEnglish
Pages (from-to)1173-1174
Number of pages2
JournalChemical Communications
Issue number11
Publication statusPublished - 7 Jun 1998

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