Investigation of novel lipid-functionalized PNA monomers as potential HIV-1 non-nucleoside reverse transcriptase and/or integrase inhibitors

Michael G. Thomas; Giovanni Maga; J. F. Mouscadet; Nicola M. Howarth

doi:10.1080/15257770701513414

Investigation of novel lipid-functionalized PNA monomers as potential HIV-1 non-nucleoside reverse transcriptase and/or integrase inhibitors

Michael G. Thomas, Giovanni Maga, J. F. Mouscadet, Nicola M. Howarth

School of Engineering & Physical Sciences

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

A range of novel N-terminal lipid-functionalized peptide nucleic acid (PNA) monomers have been prepared and their abilities to inhibit HIV-1 reverse transcriptase and integrase have been examined. Copyright © Taylor & Francis Group, LLC.

Original language	English
Pages (from-to)	1063-1066
Number of pages	4
Journal	Nucleosides, Nucleotides and Nucleic Acids
Volume	26
Issue number	8-9
DOIs	https://doi.org/10.1080/15257770701513414
Publication status	Published - Aug 2007

Keywords

Anti-HIV agents
Integrase inhibitors
Non-nucleoside reverse transcriptase inhibitors
PNA analogues

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1080/15257770701513414

Cite this

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title = "Investigation of novel lipid-functionalized PNA monomers as potential HIV-1 non-nucleoside reverse transcriptase and/or integrase inhibitors",

abstract = "A range of novel N-terminal lipid-functionalized peptide nucleic acid (PNA) monomers have been prepared and their abilities to inhibit HIV-1 reverse transcriptase and integrase have been examined. Copyright {\textcopyright} Taylor \& Francis Group, LLC.",

keywords = "Anti-HIV agents, Integrase inhibitors, Non-nucleoside reverse transcriptase inhibitors, PNA analogues",

author = "Thomas, \{Michael G.\} and Giovanni Maga and Mouscadet, \{J. F.\} and Howarth, \{Nicola M.\}",

year = "2007",

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AU - Thomas, Michael G.

AU - Maga, Giovanni

AU - Mouscadet, J. F.

AU - Howarth, Nicola M.

PY - 2007/8

Y1 - 2007/8

N2 - A range of novel N-terminal lipid-functionalized peptide nucleic acid (PNA) monomers have been prepared and their abilities to inhibit HIV-1 reverse transcriptase and integrase have been examined. Copyright © Taylor & Francis Group, LLC.

AB - A range of novel N-terminal lipid-functionalized peptide nucleic acid (PNA) monomers have been prepared and their abilities to inhibit HIV-1 reverse transcriptase and integrase have been examined. Copyright © Taylor & Francis Group, LLC.

KW - Anti-HIV agents

KW - Integrase inhibitors

KW - Non-nucleoside reverse transcriptase inhibitors

KW - PNA analogues

UR - https://www.scopus.com/pages/publications/36849043557

U2 - 10.1080/15257770701513414

DO - 10.1080/15257770701513414

M3 - Article

SN - 1525-7770

VL - 26

SP - 1063

EP - 1066

JO - Nucleosides, Nucleotides and Nucleic Acids

JF - Nucleosides, Nucleotides and Nucleic Acids

IS - 8-9

ER -

Investigation of novel lipid-functionalized PNA monomers as potential HIV-1 non-nucleoside reverse transcriptase and/or integrase inhibitors

Abstract

Keywords

UN SDGs

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