Investigation of novel lipid-functionalized PNA monomers as potential HIV-1 non-nucleoside reverse transcriptase and/or integrase inhibitors

Michael G. Thomas; Giovanni Maga; J. F. Mouscadet; Nicola M. Howarth

doi:10.1080/15257770701513414

Investigation of novel lipid-functionalized PNA monomers as potential HIV-1 non-nucleoside reverse transcriptase and/or integrase inhibitors

Michael G. Thomas, Giovanni Maga, J. F. Mouscadet, Nicola M. Howarth

School of Engineering & Physical Sciences

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

A range of novel N-terminal lipid-functionalized peptide nucleic acid (PNA) monomers have been prepared and their abilities to inhibit HIV-1 reverse transcriptase and integrase have been examined. Copyright © Taylor & Francis Group, LLC.

Original language	English
Pages (from-to)	1063-1066
Number of pages	4
Journal	Nucleosides, Nucleotides and Nucleic Acids
Volume	26
Issue number	8-9
DOIs	https://doi.org/10.1080/15257770701513414
Publication status	Published - Aug 2007

Keywords

Anti-HIV agents
Integrase inhibitors
Non-nucleoside reverse transcriptase inhibitors
PNA analogues

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1080/15257770701513414

Cite this

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title = "Investigation of novel lipid-functionalized PNA monomers as potential HIV-1 non-nucleoside reverse transcriptase and/or integrase inhibitors",

abstract = "A range of novel N-terminal lipid-functionalized peptide nucleic acid (PNA) monomers have been prepared and their abilities to inhibit HIV-1 reverse transcriptase and integrase have been examined. Copyright {\textcopyright} Taylor & Francis Group, LLC.",

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author = "Thomas, {Michael G.} and Giovanni Maga and Mouscadet, {J. F.} and Howarth, {Nicola M.}",

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AU - Thomas, Michael G.

AU - Maga, Giovanni

AU - Mouscadet, J. F.

AU - Howarth, Nicola M.

PY - 2007/8

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AB - A range of novel N-terminal lipid-functionalized peptide nucleic acid (PNA) monomers have been prepared and their abilities to inhibit HIV-1 reverse transcriptase and integrase have been examined. Copyright © Taylor & Francis Group, LLC.

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KW - Integrase inhibitors

KW - Non-nucleoside reverse transcriptase inhibitors

KW - PNA analogues

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DO - 10.1080/15257770701513414

M3 - Article

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JO - Nucleosides, Nucleotides and Nucleic Acids

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ER -

Investigation of novel lipid-functionalized PNA monomers as potential HIV-1 non-nucleoside reverse transcriptase and/or integrase inhibitors

Abstract

Keywords

UN SDGs

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