Investigation of novel lipid-functionalized PNA monomers as potential HIV-1 non-nucleoside reverse transcriptase and/or integrase inhibitors

Michael G. Thomas, Giovanni Maga, J. F. Mouscadet, Nicola M. Howarth

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

A range of novel N-terminal lipid-functionalized peptide nucleic acid (PNA) monomers have been prepared and their abilities to inhibit HIV-1 reverse transcriptase and integrase have been examined. Copyright © Taylor & Francis Group, LLC.

Original languageEnglish
Pages (from-to)1063-1066
Number of pages4
JournalNucleosides, Nucleotides and Nucleic Acids
Volume26
Issue number8-9
DOIs
Publication statusPublished - Aug 2007

Keywords

  • Anti-HIV agents
  • Integrase inhibitors
  • Non-nucleoside reverse transcriptase inhibitors
  • PNA analogues

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