Investigation of different hydrogels for nucleus replacement - A biomechanical study

Sandra Reitmaier; U. Wolfram; Anita Ignatius; Hans-Joachim Wilke; Jose M. Martin-Martinez; J. Silva-Correia; Joaquim Miguel Oliveira; R. L. Reis; Hendrik Schmidt

Investigation of different hydrogels for nucleus replacement - A biomechanical study

Sandra Reitmaier, U. Wolfram, Anita Ignatius, Hans-Joachim Wilke, Jose M. Martin-Martinez, J. Silva-Correia, Joaquim Miguel Oliveira, R. L. Reis, Hendrik Schmidt

Research output: Contribution to journal › Article › peer-review

Abstract

Hydrogels are considered promising for disc regeneration strategies. However, it is currently unknown whether the destruction of the natural interface between nucleus and surrounding
structures caused by nucleotomy and an inadequate annulus closure diminishes the mechanical competence of the disc. To clarify these mechanisms and to evaluate whether hydrogels are able to restore the biomechanical behaviour of the disc a combined in vivo and in vitro and approach was used.

Original language	English
Article number	Presentation 1394
Pages (from-to)	S51
Number of pages	1
Journal	Journal of Biomechanics
Volume	45
Publication status	Published - 2012

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title = "Investigation of different hydrogels for nucleus replacement - A biomechanical study",

abstract = "Hydrogels are considered promising for disc regeneration strategies. However, it is currently unknown whether the destruction of the natural interface between nucleus and surroundingstructures caused by nucleotomy and an inadequate annulus closure diminishes the mechanical competence of the disc. To clarify these mechanisms and to evaluate whether hydrogels are able to restore the biomechanical behaviour of the disc a combined in vivo and in vitro and approach was used. ",

author = "Sandra Reitmaier and U. Wolfram and Anita Ignatius and Hans-Joachim Wilke and Martin-Martinez, {Jose M.} and J. Silva-Correia and Oliveira, {Joaquim Miguel} and Reis, {R. L.} and Hendrik Schmidt",

note = "ESB2012: 18th Congress of the European Society of Biomechanics",

year = "2012",

language = "English",

volume = "45",

pages = "S51",

journal = "Journal of Biomechanics",

issn = "0021-9290",

publisher = "Elsevier",

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TY - JOUR

T1 - Investigation of different hydrogels for nucleus replacement - A biomechanical study

AU - Reitmaier, Sandra

AU - Wolfram, U.

AU - Ignatius, Anita

AU - Wilke, Hans-Joachim

AU - Martin-Martinez, Jose M.

AU - Silva-Correia, J.

AU - Oliveira, Joaquim Miguel

AU - Reis, R. L.

AU - Schmidt, Hendrik

N1 - ESB2012: 18th Congress of the European Society of Biomechanics

PY - 2012

Y1 - 2012

N2 - Hydrogels are considered promising for disc regeneration strategies. However, it is currently unknown whether the destruction of the natural interface between nucleus and surroundingstructures caused by nucleotomy and an inadequate annulus closure diminishes the mechanical competence of the disc. To clarify these mechanisms and to evaluate whether hydrogels are able to restore the biomechanical behaviour of the disc a combined in vivo and in vitro and approach was used.

AB - Hydrogels are considered promising for disc regeneration strategies. However, it is currently unknown whether the destruction of the natural interface between nucleus and surroundingstructures caused by nucleotomy and an inadequate annulus closure diminishes the mechanical competence of the disc. To clarify these mechanisms and to evaluate whether hydrogels are able to restore the biomechanical behaviour of the disc a combined in vivo and in vitro and approach was used.

M3 - Article

SN - 0021-9290

VL - 45

SP - S51

JO - Journal of Biomechanics

JF - Journal of Biomechanics

M1 - Presentation 1394

ER -

Investigation of different hydrogels for nucleus replacement - A biomechanical study

Abstract

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