Integrated Biomedical Device for Blood Preparation

Maïwenn Kersaudy-Kerhoas; Deirdre Kavanagh; Xiangdong Xue; Mayur Patel; Chris Bailey; Resham S. Dhariwal; M. P Y Desmulliez

doi:10.1109/ESTC.2008.4684389

Integrated Biomedical Device for Blood Preparation

Maïwenn Kersaudy-Kerhoas, Deirdre Kavanagh, Xiangdong Xue, Mayur Patel, Chris Bailey, Resham S. Dhariwal, M. P Y Desmulliez

School of Engineering & Physical Sciences

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

6 Citations (Scopus)

Abstract

The separation of red blood cells from plasma flowing in microchannels is possible by bio-physical effects such as an axial migration effect and Zweifach-Fung bifurcation law. In the present study, subchannels are placed alongside a main channel to collect cells and plasma separately. The addition of a constriction in the main microchannel creates a local high shear force region, forcing the cells to migrate and concentrate towards the centre of the channel. The resulting lab-on-a-chip was manufactured using biocompatible materials. Purity efficiency was measured for mussel and human blood suspensions as different parameters including flow rate and geometries of parent and daughter channels were varied. ©2008 IEEE.

Original language	English
Title of host publication	Proceedings - 2008 2nd Electronics Systemintegration Technology Conference, ESTC
Pages	447-452
Number of pages	6
DOIs	https://doi.org/10.1109/ESTC.2008.4684389
Publication status	Published - 2008
Event	2008 2nd Electronics Systemintegration Technology Conference - Greenwich, United Kingdom Duration: 1 Sept 2008 → 4 Sept 2008

Conference

Conference	2008 2nd Electronics Systemintegration Technology Conference
Abbreviated title	ESTC
Country/Territory	United Kingdom
City	Greenwich
Period	1/09/08 → 4/09/08

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10.1109/ESTC.2008.4684389

Cite this

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title = "Integrated Biomedical Device for Blood Preparation",

abstract = "The separation of red blood cells from plasma flowing in microchannels is possible by bio-physical effects such as an axial migration effect and Zweifach-Fung bifurcation law. In the present study, subchannels are placed alongside a main channel to collect cells and plasma separately. The addition of a constriction in the main microchannel creates a local high shear force region, forcing the cells to migrate and concentrate towards the centre of the channel. The resulting lab-on-a-chip was manufactured using biocompatible materials. Purity efficiency was measured for mussel and human blood suspensions as different parameters including flow rate and geometries of parent and daughter channels were varied. {\textcopyright}2008 IEEE.",

author = "Ma{\"i}wenn Kersaudy-Kerhoas and Deirdre Kavanagh and Xiangdong Xue and Mayur Patel and Chris Bailey and Dhariwal, {Resham S.} and Desmulliez, {M. P Y}",

year = "2008",

doi = "10.1109/ESTC.2008.4684389",

language = "English",

isbn = "9781424428144",

pages = "447--452",

booktitle = "Proceedings - 2008 2nd Electronics Systemintegration Technology Conference, ESTC",

note = "2008 2nd Electronics Systemintegration Technology Conference, ESTC ; Conference date: 01-09-2008 Through 04-09-2008",

}

Kersaudy-Kerhoas, M, Kavanagh, D, Xue, X, Patel, M, Bailey, C, Dhariwal, RS & Desmulliez, MPY 2008, Integrated Biomedical Device for Blood Preparation. in Proceedings - 2008 2nd Electronics Systemintegration Technology Conference, ESTC. pp. 447-452, 2008 2nd Electronics Systemintegration Technology Conference, Greenwich, United Kingdom, 1/09/08. https://doi.org/10.1109/ESTC.2008.4684389

TY - GEN

T1 - Integrated Biomedical Device for Blood Preparation

AU - Kersaudy-Kerhoas, Maïwenn

AU - Kavanagh, Deirdre

AU - Xue, Xiangdong

AU - Patel, Mayur

AU - Bailey, Chris

AU - Dhariwal, Resham S.

AU - Desmulliez, M. P Y

PY - 2008

Y1 - 2008

N2 - The separation of red blood cells from plasma flowing in microchannels is possible by bio-physical effects such as an axial migration effect and Zweifach-Fung bifurcation law. In the present study, subchannels are placed alongside a main channel to collect cells and plasma separately. The addition of a constriction in the main microchannel creates a local high shear force region, forcing the cells to migrate and concentrate towards the centre of the channel. The resulting lab-on-a-chip was manufactured using biocompatible materials. Purity efficiency was measured for mussel and human blood suspensions as different parameters including flow rate and geometries of parent and daughter channels were varied. ©2008 IEEE.

AB - The separation of red blood cells from plasma flowing in microchannels is possible by bio-physical effects such as an axial migration effect and Zweifach-Fung bifurcation law. In the present study, subchannels are placed alongside a main channel to collect cells and plasma separately. The addition of a constriction in the main microchannel creates a local high shear force region, forcing the cells to migrate and concentrate towards the centre of the channel. The resulting lab-on-a-chip was manufactured using biocompatible materials. Purity efficiency was measured for mussel and human blood suspensions as different parameters including flow rate and geometries of parent and daughter channels were varied. ©2008 IEEE.

UR - http://www.scopus.com/inward/record.url?scp=58149093316&partnerID=8YFLogxK

U2 - 10.1109/ESTC.2008.4684389

DO - 10.1109/ESTC.2008.4684389

M3 - Conference contribution

SN - 9781424428144

SP - 447

EP - 452

BT - Proceedings - 2008 2nd Electronics Systemintegration Technology Conference, ESTC

T2 - 2008 2nd Electronics Systemintegration Technology Conference

Y2 - 1 September 2008 through 4 September 2008

ER -

Integrated Biomedical Device for Blood Preparation

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