Inhibition of neutrophil recruitment by ES of Nippostrongylus brasiliensis

P. A. Keir, D. M. Brown, A. Clouter-Baker, Y. M. Harcus, L. Proudfoot*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)

Abstract

It has been reported that excretory-secretory (ES) material from the parasitic nematode Nippostrongylus brasiliensis has potential modulatory effects on the host's immune system. We observed that intratracheal instillation of ES from the L3 stage of the parasite reduced neutrophil numbers in LPS-induced inflammation as assessed by bronchoalveolar lavage.

Original languageEnglish
Pages (from-to)137-139
Number of pages3
JournalParasite Immunology
Volume26
Issue number3
DOIs
Publication statusPublished - Mar 2004

Keywords

  • Bronchoalveolar lavage
  • Neutrophil
  • Nippostrongylus brasiliensis

ASJC Scopus subject areas

  • Parasitology
  • Immunology

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