Indium Versus Gold Catalysis in Dehydrative Reactions with Allylic Alcohols

Stacey Webster, Louise Schaefer, Graeme Barker, Ai-Lan Lee

Research output: Contribution to journalArticle

Abstract

Indium(III) chloride can be used as a cheaper alternative to gold(I) complexes as a catalyst in dehydrative reactions with allylic alcohols. There is often an improvement in yield and, in particular, indium(III) chloride outperforms gold(I) as a catalyst in chemoselective reactions. For example, substrates with pendent alkyne or alkene groups react poorly under gold(I) catalysis, but are better tolerated under indium(III) chloride catalysis.
Original languageEnglish
Pages (from-to)2673-2678
Number of pages6
JournalSYNLETT
Volume26
Issue number19
Early online date2 Oct 2015
DOIs
Publication statusE-pub ahead of print - 2 Oct 2015

Fingerprint

Indium
Gold
Catalysis
Catalysts
Alkynes
Alkenes
Substrates
indium trichloride
allyl alcohol

Keywords

  • allylation
  • allylic alcohols
  • catalysis
  • gold
  • indium

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Webster, Stacey ; Schaefer, Louise ; Barker, Graeme ; Lee, Ai-Lan. / Indium Versus Gold Catalysis in Dehydrative Reactions with Allylic Alcohols. In: SYNLETT. 2015 ; Vol. 26, No. 19. pp. 2673-2678.
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Indium Versus Gold Catalysis in Dehydrative Reactions with Allylic Alcohols. / Webster, Stacey; Schaefer, Louise; Barker, Graeme; Lee, Ai-Lan.

In: SYNLETT, Vol. 26, No. 19, 02.10.2015, p. 2673-2678.

Research output: Contribution to journalArticle

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