Importance of Surface Coating on Accumulation Dynamics and Acute Toxicity of Copper Nanomaterials and Dissolved Copper to Daphnia magna

Zuzanna Anna Gajda-Meissner, Konrad Matyja, David Brown, Mark G. J. Hartl, Teresa F. Fernandes

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Abstract

In this study the effect of copper oxide nanomaterials (CuO NMs), uncoated and with three different surface coatings (i.e. carboxylated, pegylated and ammonia Importance of surface coating on accumulation dynamics and acute toxicity of copper nanomaterials and dissolved copper to Daphnia magna groups), was evaluated on acute toxicity and accumulation dynamics in Daphnia magna. Biosorption and elimination rate constants were determined for D. magna following waterborne exposure to dissolved copper and copper oxide NMs using biodynamic modeling. The relationship between modeled parameters and acute toxicity endpoints was evaluated to investigate if accumulation dynamics parameters could be used as a predictor of acute toxicity. The Langmuir equation was used to characterize the biosorption dynamics of copper NMs and copper chloride, used as dissolved copper control. Uptake rates showed the following ranking: pristine-CuO NMs > NH3-CuO NMs > aqueous Cu > PEG-CuO NMs > COOH-CuO NMs. To determine copper elimination by D. magna a one compartment model was used. Different elimination rate constants were estimated for each chemical substance tested. Those which were easily biosorbed were also easily removed from organisms. Biosorption and depuration properties of NMs were correlated with zeta potential values and diameter of NMs agglomerates in the suspensions. There is no link between biosorption and toxicity. Waterborne exposures to more difficult to biosorb CuO NMs are likely to induce adverse effects more than those which are easily to biosorb. It is proposed that some physicochemical properties of NMs in media, including zeta potential and agglomerate diameter, can lead to higher biosorption but do not necessarily affect toxicity. The mode of interaction of the NMs with the organism, seems to be complex and depends on chemical speciation and physicochemical properties of NMs inside an organism. Moreover our findings highlight that coating type affects the biosorption dynamics, depuration kinetics and dissolution rate of NMs in media.
Original languageEnglish
JournalEnvironmental Toxicology and Chemistry
Early online date14 Oct 2019
DOIs
Publication statusE-pub ahead of print - 14 Oct 2019

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coating
copper
toxicity
depuration
oxide
chemical substance
speciation (chemistry)
physicochemical property
ranking
ammonia
chloride
kinetics
rate
organism

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title = "Importance of Surface Coating on Accumulation Dynamics and Acute Toxicity of Copper Nanomaterials and Dissolved Copper to Daphnia magna",
abstract = "In this study the effect of copper oxide nanomaterials (CuO NMs), uncoated and with three different surface coatings (i.e. carboxylated, pegylated and ammonia Importance of surface coating on accumulation dynamics and acute toxicity of copper nanomaterials and dissolved copper to Daphnia magna groups), was evaluated on acute toxicity and accumulation dynamics in Daphnia magna. Biosorption and elimination rate constants were determined for D. magna following waterborne exposure to dissolved copper and copper oxide NMs using biodynamic modeling. The relationship between modeled parameters and acute toxicity endpoints was evaluated to investigate if accumulation dynamics parameters could be used as a predictor of acute toxicity. The Langmuir equation was used to characterize the biosorption dynamics of copper NMs and copper chloride, used as dissolved copper control. Uptake rates showed the following ranking: pristine-CuO NMs > NH3-CuO NMs > aqueous Cu > PEG-CuO NMs > COOH-CuO NMs. To determine copper elimination by D. magna a one compartment model was used. Different elimination rate constants were estimated for each chemical substance tested. Those which were easily biosorbed were also easily removed from organisms. Biosorption and depuration properties of NMs were correlated with zeta potential values and diameter of NMs agglomerates in the suspensions. There is no link between biosorption and toxicity. Waterborne exposures to more difficult to biosorb CuO NMs are likely to induce adverse effects more than those which are easily to biosorb. It is proposed that some physicochemical properties of NMs in media, including zeta potential and agglomerate diameter, can lead to higher biosorption but do not necessarily affect toxicity. The mode of interaction of the NMs with the organism, seems to be complex and depends on chemical speciation and physicochemical properties of NMs inside an organism. Moreover our findings highlight that coating type affects the biosorption dynamics, depuration kinetics and dissolution rate of NMs in media.",
author = "Gajda-Meissner, {Zuzanna Anna} and Konrad Matyja and David Brown and Hartl, {Mark G. J.} and Fernandes, {Teresa F.}",
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T1 - Importance of Surface Coating on Accumulation Dynamics and Acute Toxicity of Copper Nanomaterials and Dissolved Copper to Daphnia magna

AU - Gajda-Meissner, Zuzanna Anna

AU - Matyja, Konrad

AU - Brown, David

AU - Hartl, Mark G. J.

AU - Fernandes, Teresa F.

PY - 2019/10/14

Y1 - 2019/10/14

N2 - In this study the effect of copper oxide nanomaterials (CuO NMs), uncoated and with three different surface coatings (i.e. carboxylated, pegylated and ammonia Importance of surface coating on accumulation dynamics and acute toxicity of copper nanomaterials and dissolved copper to Daphnia magna groups), was evaluated on acute toxicity and accumulation dynamics in Daphnia magna. Biosorption and elimination rate constants were determined for D. magna following waterborne exposure to dissolved copper and copper oxide NMs using biodynamic modeling. The relationship between modeled parameters and acute toxicity endpoints was evaluated to investigate if accumulation dynamics parameters could be used as a predictor of acute toxicity. The Langmuir equation was used to characterize the biosorption dynamics of copper NMs and copper chloride, used as dissolved copper control. Uptake rates showed the following ranking: pristine-CuO NMs > NH3-CuO NMs > aqueous Cu > PEG-CuO NMs > COOH-CuO NMs. To determine copper elimination by D. magna a one compartment model was used. Different elimination rate constants were estimated for each chemical substance tested. Those which were easily biosorbed were also easily removed from organisms. Biosorption and depuration properties of NMs were correlated with zeta potential values and diameter of NMs agglomerates in the suspensions. There is no link between biosorption and toxicity. Waterborne exposures to more difficult to biosorb CuO NMs are likely to induce adverse effects more than those which are easily to biosorb. It is proposed that some physicochemical properties of NMs in media, including zeta potential and agglomerate diameter, can lead to higher biosorption but do not necessarily affect toxicity. The mode of interaction of the NMs with the organism, seems to be complex and depends on chemical speciation and physicochemical properties of NMs inside an organism. Moreover our findings highlight that coating type affects the biosorption dynamics, depuration kinetics and dissolution rate of NMs in media.

AB - In this study the effect of copper oxide nanomaterials (CuO NMs), uncoated and with three different surface coatings (i.e. carboxylated, pegylated and ammonia Importance of surface coating on accumulation dynamics and acute toxicity of copper nanomaterials and dissolved copper to Daphnia magna groups), was evaluated on acute toxicity and accumulation dynamics in Daphnia magna. Biosorption and elimination rate constants were determined for D. magna following waterborne exposure to dissolved copper and copper oxide NMs using biodynamic modeling. The relationship between modeled parameters and acute toxicity endpoints was evaluated to investigate if accumulation dynamics parameters could be used as a predictor of acute toxicity. The Langmuir equation was used to characterize the biosorption dynamics of copper NMs and copper chloride, used as dissolved copper control. Uptake rates showed the following ranking: pristine-CuO NMs > NH3-CuO NMs > aqueous Cu > PEG-CuO NMs > COOH-CuO NMs. To determine copper elimination by D. magna a one compartment model was used. Different elimination rate constants were estimated for each chemical substance tested. Those which were easily biosorbed were also easily removed from organisms. Biosorption and depuration properties of NMs were correlated with zeta potential values and diameter of NMs agglomerates in the suspensions. There is no link between biosorption and toxicity. Waterborne exposures to more difficult to biosorb CuO NMs are likely to induce adverse effects more than those which are easily to biosorb. It is proposed that some physicochemical properties of NMs in media, including zeta potential and agglomerate diameter, can lead to higher biosorption but do not necessarily affect toxicity. The mode of interaction of the NMs with the organism, seems to be complex and depends on chemical speciation and physicochemical properties of NMs inside an organism. Moreover our findings highlight that coating type affects the biosorption dynamics, depuration kinetics and dissolution rate of NMs in media.

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JO - Environmental Toxicology and Chemistry

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SN - 0730-7268

ER -