Catalytic hydrogenation (H2, Pd-C) of the epoxide (5a) gives the dione derivative (6); an analogous procedure (5d)? (7) has been used in a sequence (5b)?(5c)?(5d)?(7)?(2d)?(2b) to give a valuable intermediate (2b) for the synthesis of 4,11-dideoxyanthracyclinones: implications for interconversions in the anthracyclinone series are described.
|Number of pages||2|
|Journal||Journal of the Chemical Society, Chemical Communications|
|Publication status||Published - 1984|