Abstract
The composition of the gut microbiota has been linked to acute stressors, suggesting that modulation of the gut microbiome is a potential avenue for enhancing human health and performance. The gut microbiome exerts its effects through several metabolites, which induce epigenetic and metabolic changes. Stress is a common occurrence in humans facing challenging environments such as military personnel and astronauts, but is not limited to humans. Among various species, crocodiles are well known for their "hardiness" and ability to achieve longevity, while surviving under stressful conditions. We speculated that their microbial gut flora produces substances contributing to their ability to resist stress, "wellbeing" and "longevity". Herein, we deliberate upon the stressors faced by individuals in testing conditions, and discuss potential avenues that can mitigate the gut microbiome compositional changes in order to augment human performance and overall health.
| Original language | English |
|---|---|
| Article number | 2583020 |
| Journal | Future Science OA |
| Volume | 11 |
| Issue number | 1 |
| Early online date | 11 Nov 2025 |
| DOIs | |
| Publication status | Published - 31 Dec 2025 |
Keywords
- Gut microbiome
- human performance
- environmental stress
- circadian rhythms
- crocodile microbiome
- resilient species
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© 2025 the Author(s). Published by informa uK Limited, trading as taylor & Francis Group This is an Open Access article distributed under the terms of the creative commons Attribution-noncommercial License (http://creativecommons.org/licenses/by-nc/4.0/),which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. the terms on which this articlehas been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.