GuLF DREAM

A Model to Estimate Dermal Exposure Among Oil Spill Response and Clean-up Workers

Melanie Gorman Ng, John W Cherrie, Anne Sleeuwenhoek, Mark Stenzel, Richard K. Kwok, Lawrence S. Engel, Jennifer M. Cavallari, Aaron Blair, Dale P. Sandler, Patricia Stewart

Research output: Contribution to journalArticle

Abstract

Tens of thousands of individuals performed oil spill response and clean-up (OSRC) activities following the 'Deepwater Horizon' oil drilling rig explosion in 2010. Many were exposed to oil residues and dispersants. The US National Institute of Environmental Health Sciences assembled a cohort of nearly 33 000 workers to investigate potential adverse health effects of oil spill exposures. Estimates of dermal and inhalation exposure are required for those individuals. Ambient breathing-zone measurements taken at the time of the spill were used to estimate inhalation exposures for participants in the GuLF STUDY (Gulf Long-term Follow-up Study), but no dermal measurements were collected. Consequently, a modelling approach was used to estimate dermal exposures. We sought to modify DREAM (DeRmal Exposure Assessment Method) to optimize the model for assessing exposure to various oil spill-related substances and to incorporate advances in dermal exposure research. Each DREAM parameter was reviewed in the context of literature published since 2000 and modified where appropriate. To reflect the environment in which the OSRC work took place, the model treatment of evaporation was expanded to include vapour pressure and wind speed, and the effect of seawater on exposure was added. The modified model is called GuLF DREAM and exposure is estimated in GuLF DREAM units (GDU). An external validation to assess the performance of the model for oils, tars, and fuels was conducted using available published dermal wipe measurements of heavy fuel oil (HFO) and dermal hand wash measurements of asphalt. Overall, measured exposures had moderate correlations with GDU estimates (r = 0.59) with specific correlations of -0.48 for HFO and 0.68 for asphalt. The GuLF DREAM model described in this article has been used to generate dermal exposure estimates for the GuLF STUDY. Many of the updates made were generic, so the updated model may be useful for other dermal exposure scenarios.

Original languageEnglish
JournalAnnals of Work Exposures and Health
Early online date23 Jul 2019
DOIs
Publication statusE-pub ahead of print - 23 Jul 2019

Fingerprint

Petroleum Pollution
Skin
asphalt
Fuel Oils
Inhalation Exposure
Oils
National Institute of Environmental Health Sciences (U.S.)
Vapor Pressure
Tars
Explosions
Seawater
Workplace

Cite this

Gorman Ng, Melanie ; Cherrie, John W ; Sleeuwenhoek, Anne ; Stenzel, Mark ; Kwok, Richard K. ; Engel, Lawrence S. ; Cavallari, Jennifer M. ; Blair, Aaron ; Sandler, Dale P. ; Stewart, Patricia. / GuLF DREAM : A Model to Estimate Dermal Exposure Among Oil Spill Response and Clean-up Workers. In: Annals of Work Exposures and Health. 2019.
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Gorman Ng, M, Cherrie, JW, Sleeuwenhoek, A, Stenzel, M, Kwok, RK, Engel, LS, Cavallari, JM, Blair, A, Sandler, DP & Stewart, P 2019, 'GuLF DREAM: A Model to Estimate Dermal Exposure Among Oil Spill Response and Clean-up Workers', Annals of Work Exposures and Health. https://doi.org/10.1093/annweh/wxz037

GuLF DREAM : A Model to Estimate Dermal Exposure Among Oil Spill Response and Clean-up Workers. / Gorman Ng, Melanie; Cherrie, John W; Sleeuwenhoek, Anne; Stenzel, Mark; Kwok, Richard K.; Engel, Lawrence S.; Cavallari, Jennifer M.; Blair, Aaron; Sandler, Dale P.; Stewart, Patricia.

In: Annals of Work Exposures and Health, 23.07.2019.

Research output: Contribution to journalArticle

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T2 - A Model to Estimate Dermal Exposure Among Oil Spill Response and Clean-up Workers

AU - Gorman Ng, Melanie

AU - Cherrie, John W

AU - Sleeuwenhoek, Anne

AU - Stenzel, Mark

AU - Kwok, Richard K.

AU - Engel, Lawrence S.

AU - Cavallari, Jennifer M.

AU - Blair, Aaron

AU - Sandler, Dale P.

AU - Stewart, Patricia

PY - 2019/7/23

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AB - Tens of thousands of individuals performed oil spill response and clean-up (OSRC) activities following the 'Deepwater Horizon' oil drilling rig explosion in 2010. Many were exposed to oil residues and dispersants. The US National Institute of Environmental Health Sciences assembled a cohort of nearly 33 000 workers to investigate potential adverse health effects of oil spill exposures. Estimates of dermal and inhalation exposure are required for those individuals. Ambient breathing-zone measurements taken at the time of the spill were used to estimate inhalation exposures for participants in the GuLF STUDY (Gulf Long-term Follow-up Study), but no dermal measurements were collected. Consequently, a modelling approach was used to estimate dermal exposures. We sought to modify DREAM (DeRmal Exposure Assessment Method) to optimize the model for assessing exposure to various oil spill-related substances and to incorporate advances in dermal exposure research. Each DREAM parameter was reviewed in the context of literature published since 2000 and modified where appropriate. To reflect the environment in which the OSRC work took place, the model treatment of evaporation was expanded to include vapour pressure and wind speed, and the effect of seawater on exposure was added. The modified model is called GuLF DREAM and exposure is estimated in GuLF DREAM units (GDU). An external validation to assess the performance of the model for oils, tars, and fuels was conducted using available published dermal wipe measurements of heavy fuel oil (HFO) and dermal hand wash measurements of asphalt. Overall, measured exposures had moderate correlations with GDU estimates (r = 0.59) with specific correlations of -0.48 for HFO and 0.68 for asphalt. The GuLF DREAM model described in this article has been used to generate dermal exposure estimates for the GuLF STUDY. Many of the updates made were generic, so the updated model may be useful for other dermal exposure scenarios.

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