The rate of fermentation of glucose by a polyploid strain of Saccharomyces cerevisiae growing in a defined salts medium depends on the availability of NH4+. Its decline after exhaustion of the nitrogen source correspond with the ability of the cells to accumulate the glucose analogue 2-deoxyglucose. Addition of NH4+ to a nitrogen-depleted culture stimulated both glucose utilization and 2-deoxyglucose uptake. Since stimulation was inhibited by cycloheximide, maintenance of glucose transport during fermentation is dependent on protein synthesis.
|Number of pages||3|
|Journal||Letters in Applied Microbiology|
|Publication status||Published - 1991|