Gas Phase Fluorescence Analysis

David Carty (Inventor), Eckart Wrede (Inventor), Nils Hendrik Nahler (Inventor)

Research output: Patent


A method and apparatus for quantifying an analyte in a gas phase or liquid sample comprises: a pulsed or continuous, coherent or incoherent light source (10), a pair of reflective mirrors (13) located on the optical axis forming an optical cavity, and a cell (4) located between the mirrors (13), the cell (4) having a gas inlet (3) and a gas outlet (5); a fluorescence detector (17) located off the cavity axis and arranged to provide a first signal in response to fluorescence within the cavity; a photon detector (14) located axially external to the cavity and arranged to provide a second signal; wherein the apparatus including the axial photon detector (14) is configured to comprise a cavity enhanced absorption spectrometer; wherein apparatus including the off-axis photon detector is configured to comprise a cavity-enhanced laser-induced fluorescence (CELIF) spectrophotometer; means for supplying a pure sample or an analyte-containing sample to the cavity; a processor (9) adapted to receive a first signal to calibrate the apparatus and to receive a second signal to provide a measurement of the concentration of the analyte in the sample.
Original languageEnglish
Patent numberWO/2017/021424
IPCA61B 5/00 (2006.01), A61B 5/08 (2006.01), G01N 33/00 (2006.01), G01N 21/31 (2006.01), G01N 21/64 (2006.01)
Priority date3/08/15
Publication statusPublished - 9 Feb 2017


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