Frontal operculum temporal difference signals and social motor response learning

Poornima Kumar, Gordon Waiter, Trevor Ahearn, Maarten Milders, Ian Reid, J. Douglas Steele

    Research output: Contribution to journalArticle

    Abstract

    Substantial experimental evidence Supports the theory that the dopaminergic system codes a phasic (short duration) signal predicting the delivery of primary reinforcers, such as water when thirsty, during Pavlovian learning. This signal is described by the temporal difference (TD) model. Recently, it has been suggested that the human dopaminergic system also codes more complex cognitive goal states, including those required for human social interaction. Using functional magnetic resonance imaging (fMRI) with 18 healthy subjects, we tested the hypothesis that TD signals would be present during a Pavlovian learning task, and during a social motor response learning task. Using an identical model, TD signals were present in both tasks, although in different brain regions. Specifically, signals were present in the dorsal anterior cingulate, ventral striatum, amygdala, and thalamus with Pavlovian learning, and the dorsal anterior cingulate and bilateral frontal operculum with social motor response learning. The frontal operculum is believed to be the human homologue of the monkey mirror neuron system, and there is evidence which links the region with inference about other peoples' intentions and goals. The results support the contention that the human dopaminergic system predicts both primary reinforcers, and more complex cognitive goal states, such as motor responses required for human social group interaction. Dysfunction of such a mechanism might be associated with abnormal affective responses and incorrect social predictions, as Occur in psychiatric disorders. Hum Brain Mapp 30:1421-1430, 2009. (C) 2008 Wiley-Liss, Inc.

    Original languageEnglish
    Pages (from-to)1421-1430
    Number of pages10
    JournalHuman Brain Mapping
    Volume30
    Issue number5
    DOIs
    Publication statusPublished - May 2009

    Cite this

    Kumar, P., Waiter, G., Ahearn, T., Milders, M., Reid, I., & Steele, J. D. (2009). Frontal operculum temporal difference signals and social motor response learning. Human Brain Mapping, 30(5), 1421-1430. https://doi.org/10.1002/hbm.20611
    Kumar, Poornima ; Waiter, Gordon ; Ahearn, Trevor ; Milders, Maarten ; Reid, Ian ; Steele, J. Douglas. / Frontal operculum temporal difference signals and social motor response learning. In: Human Brain Mapping. 2009 ; Vol. 30, No. 5. pp. 1421-1430.
    @article{5cfa08b54b0b43fa8048f3e6996834db,
    title = "Frontal operculum temporal difference signals and social motor response learning",
    abstract = "Substantial experimental evidence Supports the theory that the dopaminergic system codes a phasic (short duration) signal predicting the delivery of primary reinforcers, such as water when thirsty, during Pavlovian learning. This signal is described by the temporal difference (TD) model. Recently, it has been suggested that the human dopaminergic system also codes more complex cognitive goal states, including those required for human social interaction. Using functional magnetic resonance imaging (fMRI) with 18 healthy subjects, we tested the hypothesis that TD signals would be present during a Pavlovian learning task, and during a social motor response learning task. Using an identical model, TD signals were present in both tasks, although in different brain regions. Specifically, signals were present in the dorsal anterior cingulate, ventral striatum, amygdala, and thalamus with Pavlovian learning, and the dorsal anterior cingulate and bilateral frontal operculum with social motor response learning. The frontal operculum is believed to be the human homologue of the monkey mirror neuron system, and there is evidence which links the region with inference about other peoples' intentions and goals. The results support the contention that the human dopaminergic system predicts both primary reinforcers, and more complex cognitive goal states, such as motor responses required for human social group interaction. Dysfunction of such a mechanism might be associated with abnormal affective responses and incorrect social predictions, as Occur in psychiatric disorders. Hum Brain Mapp 30:1421-1430, 2009. (C) 2008 Wiley-Liss, Inc.",
    author = "Poornima Kumar and Gordon Waiter and Trevor Ahearn and Maarten Milders and Ian Reid and Steele, {J. Douglas}",
    year = "2009",
    month = "5",
    doi = "10.1002/hbm.20611",
    language = "English",
    volume = "30",
    pages = "1421--1430",
    journal = "Human Brain Mapping",
    issn = "1065-9471",
    publisher = "Wiley-Liss Inc.",
    number = "5",

    }

    Kumar, P, Waiter, G, Ahearn, T, Milders, M, Reid, I & Steele, JD 2009, 'Frontal operculum temporal difference signals and social motor response learning', Human Brain Mapping, vol. 30, no. 5, pp. 1421-1430. https://doi.org/10.1002/hbm.20611

    Frontal operculum temporal difference signals and social motor response learning. / Kumar, Poornima; Waiter, Gordon; Ahearn, Trevor; Milders, Maarten; Reid, Ian; Steele, J. Douglas.

    In: Human Brain Mapping, Vol. 30, No. 5, 05.2009, p. 1421-1430.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Frontal operculum temporal difference signals and social motor response learning

    AU - Kumar, Poornima

    AU - Waiter, Gordon

    AU - Ahearn, Trevor

    AU - Milders, Maarten

    AU - Reid, Ian

    AU - Steele, J. Douglas

    PY - 2009/5

    Y1 - 2009/5

    N2 - Substantial experimental evidence Supports the theory that the dopaminergic system codes a phasic (short duration) signal predicting the delivery of primary reinforcers, such as water when thirsty, during Pavlovian learning. This signal is described by the temporal difference (TD) model. Recently, it has been suggested that the human dopaminergic system also codes more complex cognitive goal states, including those required for human social interaction. Using functional magnetic resonance imaging (fMRI) with 18 healthy subjects, we tested the hypothesis that TD signals would be present during a Pavlovian learning task, and during a social motor response learning task. Using an identical model, TD signals were present in both tasks, although in different brain regions. Specifically, signals were present in the dorsal anterior cingulate, ventral striatum, amygdala, and thalamus with Pavlovian learning, and the dorsal anterior cingulate and bilateral frontal operculum with social motor response learning. The frontal operculum is believed to be the human homologue of the monkey mirror neuron system, and there is evidence which links the region with inference about other peoples' intentions and goals. The results support the contention that the human dopaminergic system predicts both primary reinforcers, and more complex cognitive goal states, such as motor responses required for human social group interaction. Dysfunction of such a mechanism might be associated with abnormal affective responses and incorrect social predictions, as Occur in psychiatric disorders. Hum Brain Mapp 30:1421-1430, 2009. (C) 2008 Wiley-Liss, Inc.

    AB - Substantial experimental evidence Supports the theory that the dopaminergic system codes a phasic (short duration) signal predicting the delivery of primary reinforcers, such as water when thirsty, during Pavlovian learning. This signal is described by the temporal difference (TD) model. Recently, it has been suggested that the human dopaminergic system also codes more complex cognitive goal states, including those required for human social interaction. Using functional magnetic resonance imaging (fMRI) with 18 healthy subjects, we tested the hypothesis that TD signals would be present during a Pavlovian learning task, and during a social motor response learning task. Using an identical model, TD signals were present in both tasks, although in different brain regions. Specifically, signals were present in the dorsal anterior cingulate, ventral striatum, amygdala, and thalamus with Pavlovian learning, and the dorsal anterior cingulate and bilateral frontal operculum with social motor response learning. The frontal operculum is believed to be the human homologue of the monkey mirror neuron system, and there is evidence which links the region with inference about other peoples' intentions and goals. The results support the contention that the human dopaminergic system predicts both primary reinforcers, and more complex cognitive goal states, such as motor responses required for human social group interaction. Dysfunction of such a mechanism might be associated with abnormal affective responses and incorrect social predictions, as Occur in psychiatric disorders. Hum Brain Mapp 30:1421-1430, 2009. (C) 2008 Wiley-Liss, Inc.

    U2 - 10.1002/hbm.20611

    DO - 10.1002/hbm.20611

    M3 - Article

    VL - 30

    SP - 1421

    EP - 1430

    JO - Human Brain Mapping

    JF - Human Brain Mapping

    SN - 1065-9471

    IS - 5

    ER -

    Kumar P, Waiter G, Ahearn T, Milders M, Reid I, Steele JD. Frontal operculum temporal difference signals and social motor response learning. Human Brain Mapping. 2009 May;30(5):1421-1430. https://doi.org/10.1002/hbm.20611