Fractal texture analysis: an aid to tissue characterisation with intravascular ultrasound

W H Nailon, Steve McLaughlin, T Spencer, M P Ramo, D M Salter, G R Sutherland, E A Fox, W. Norman McDicken

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Coronary artery disease is a condition responsible for many acute coronary syndromes. The ability to categorise diseased arterial tissue belonging to distinct pathological groups would contribute to the understanding of the pathophysiologic structure of individual lesions, as well as making a significant contribution to treatment choice. Here, we investigate the use of fractal texture analysis techniques to assess the ability of 30MHz intravascular ultrasound (IVUS) data, in raw form, to characterise intracoronary disease from samples of: foam cells (FC); foam cells containing lipid (LIP-FC) and loose fibrotic tissue (LFT). Histological analysis was used to form a gold standard from which the results were verified. The results show inadequate discrimination of the sub-groups studied but highlight the need for a less comprehensive list of disease categories for discrimination with IVUS, where, it would appear that the resolution limitations of the imaging system prevent the original sub-groups defined by histological examination from being observed.

Original languageEnglish
Title of host publicationProceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 1997
PublisherIEEE
Pages534-537
Number of pages4
Volume2
ISBN (Print)0-7803-4262-3
DOIs
Publication statusPublished - 1997
Event19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Chicago
Duration: 30 Oct 19972 Nov 1997

Conference

Conference19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
CityChicago
Period30/10/972/11/97

Cite this