Fibre-based ratiometric fluorescence imaging for contrast enhancement of spectrally similar signals in the lung

Helen E. Parker; James Stone; Adam D. L. Marshall; Tushar R. Choudhary; Robert R. Thomson; Kevin Dhaliwal; Michael G. Tanner

doi:10.1364/TRANSLATIONAL.2020.TTu2B.4

Fibre-based ratiometric fluorescence imaging for contrast enhancement of spectrally similar signals in the lung

Helen E. Parker, James Stone, Adam D. L. Marshall, Tushar R. Choudhary, Robert R. Thomson, Kevin Dhaliwal, Michael G. Tanner

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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Abstract

We present a widefield ratiometric fibred optical endomicroscopy platform capable of enhancing contrast between spectrally similar pathologically relevant fluorophores. We demonstrate the detection of fluorescently labelled bacteria in an autofluorescent ex vivo human lung model.

Original language	English
Title of host publication	Clinical and Translational Biophotonics 2020
Publisher	OSA Publishing
ISBN (Print)	9781943580743
DOIs	https://doi.org/10.1364/TRANSLATIONAL.2020.TTu2B.4
Publication status	Published - 2020

Keywords

Endomicroscopy
Fiber bundles
Fluorescence
Fluorescence lifetime imaging
Image processing
In vivo imaging

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10.1364/TRANSLATIONAL.2020.TTu2B.4

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title = "Fibre-based ratiometric fluorescence imaging for contrast enhancement of spectrally similar signals in the lung",

abstract = "We present a widefield ratiometric fibred optical endomicroscopy platform capable of enhancing contrast between spectrally similar pathologically relevant fluorophores. We demonstrate the detection of fluorescently labelled bacteria in an autofluorescent ex vivo human lung model.",

keywords = "Endomicroscopy, Fiber bundles, Fluorescence, Fluorescence lifetime imaging, Image processing, In vivo imaging",

author = "Parker, {Helen E.} and James Stone and Marshall, {Adam D. L.} and Choudhary, {Tushar R.} and Thomson, {Robert R.} and Kevin Dhaliwal and Tanner, {Michael G.}",

year = "2020",

doi = "10.1364/TRANSLATIONAL.2020.TTu2B.4",

language = "English",

isbn = "9781943580743",

booktitle = "Clinical and Translational Biophotonics 2020",

publisher = "OSA Publishing",

address = "United States",

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T1 - Fibre-based ratiometric fluorescence imaging for contrast enhancement of spectrally similar signals in the lung

AU - Parker, Helen E.

AU - Stone, James

AU - Marshall, Adam D. L.

AU - Choudhary, Tushar R.

AU - Thomson, Robert R.

AU - Dhaliwal, Kevin

AU - Tanner, Michael G.

PY - 2020

Y1 - 2020

N2 - We present a widefield ratiometric fibred optical endomicroscopy platform capable of enhancing contrast between spectrally similar pathologically relevant fluorophores. We demonstrate the detection of fluorescently labelled bacteria in an autofluorescent ex vivo human lung model.

AB - We present a widefield ratiometric fibred optical endomicroscopy platform capable of enhancing contrast between spectrally similar pathologically relevant fluorophores. We demonstrate the detection of fluorescently labelled bacteria in an autofluorescent ex vivo human lung model.

KW - Endomicroscopy

KW - Fiber bundles

KW - Fluorescence

KW - Fluorescence lifetime imaging

KW - Image processing

KW - In vivo imaging

UR - http://www.scopus.com/inward/record.url?scp=85091399309&partnerID=8YFLogxK

U2 - 10.1364/TRANSLATIONAL.2020.TTu2B.4

DO - 10.1364/TRANSLATIONAL.2020.TTu2B.4

M3 - Conference contribution

SN - 9781943580743

BT - Clinical and Translational Biophotonics 2020

PB - OSA Publishing

ER -

Fibre-based ratiometric fluorescence imaging for contrast enhancement of spectrally similar signals in the lung

Abstract

Keywords

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