Feature selection and classification in bioscience/medical datasets: Study of parameters and multi-objective approach in two-phase EA/k-NN method

M. S B Dissanayake, David W. Corne

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

Feature selection continues to grow in importance in many areas of science and engineering, as large datasets become increasingly common. In particular, bioscience and medical datasets routinely contain several thousands of features. For effective data mining in such datasets, tools are required that can reliably distinguish the most relevant features. The latter is a useful goal in itself (e.g. such features may be putative drug targets), and also improves (perhaps drastically) both the speed of machine learning algorithms on the dataset, and the quality of predictive models. Among much research in feature selection methods, previous work has shown promise for an evolutionary algorithm/classifier combination (EA/k-NN), which, in successive phases of the same algorithm, serves first as the feature selection mechanism and second as the machine learning method yielding an accurate classifier. Here, we follow up that work by investigating the configuration and parametrisation of the two phases, including an investigation of multi-objective approaches for one or both phases. Following tests on three datasets, we find: further evidence that the two-phase approach is effective, with results on the most difficult dataset highly competitive with the literature; inconclusive results concerning the ideal way to configure the two phases; evidence in support of using a multi-objective approach in one or both phases.

Original languageEnglish
Title of host publication2010 UK Workshop on Computational Intelligence, UKCI 2010
DOIs
Publication statusPublished - 2010
Event2010 UK Workshop on Computational Intelligence - Colchester, United Kingdom
Duration: 8 Sep 201010 Sep 2010

Conference

Conference2010 UK Workshop on Computational Intelligence
Abbreviated titleUKCI 2010
CountryUnited Kingdom
CityColchester
Period8/09/1010/09/10

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