In this study, the evolution of fabric in compacted London Clay has been studied in detail. Samples were statically compacted to the same initial conditions and taken along a number of stress paths - involving both wetting and loading - to different final conditions. Wetting and loading was conducted using both conventional and osmotic oedometers (the latter allowed the suction to be varied in a controlled manner). The study of micro-fabric involved a combination of quantitative measurements of the pore space, using Mercury Intrusion Porosimetry, with qualitative observations of the overall arrangement of particles, using Environmental Scanning Electron Microscopy. The study showed important changes to take place in the soil micro-fabric during wetting, whereas the effect of loading was seen to be less severe. The results suggest that changes in the overall micro-fabric of a compacted clayey soil are strongly stress path dependent.