Abstract
Under conditions of kinetic control, the cis-diastereoselectivity of the Pictet-Spengler reaction between tryptophan esters and aldehydes can be controlled by varying the size of the ester group; the reaction proceeds in essentially quantitative yield with most aldehydes when conducted in chloroform in the presence of molecular sieves.
Original language | English |
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Pages (from-to) | 3587-3588 |
Number of pages | 2 |
Journal | Tetrahedron Letters |
Volume | 35 |
Issue number | 21 |
DOIs | |
Publication status | Published - 1994 |