The budding yeast Saccharomyces cerevisiae and the fission yeast Schizosaccharomyces pombe were grown under CO2 pressure. Cell division was inhibited in both yeasts; RNA and protein content per cell declined but DNA continued to be synthesized and, in the case of Sacch. cerevisiae, reached twice the normal level within 24 h. Changes in mean cell volume occurred in both yeasts within 1 h; an increase occurred in the budding yeast while a decrease was observed in the fission yeast. The results suggest that CO2 may exert its influence on cell characteristics through a change in cell volume.
|Number of pages
|Journal of General Microbiology
|Published - 1987