Effects of adrenergic agonists and antagonists and of the catechol nucleus on the Na+, K+-ATPase and Mg2+-ATPase activities of synaptosomes

A H Sawas; John C Gilbert

doi:10.1016/0006-2952(81)90013-7

Effects of adrenergic agonists and antagonists and of the catechol nucleus on the Na⁺, K⁺-ATPase and Mg²⁺-ATPase activities of synaptosomes

A H Sawas, John C Gilbert

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

The effects of adrenergic agonists, antagonists and other drugs on the Na⁺, K⁺-ATPase and Mg²⁺-ATPase activities of rat cerebral cortex synaptosomes have been determined. Noradrenaline, isoprenaline, dopamine, 1-DOPA and catechol stimulated the activities of the enzymes. The stimulatory effects were not prevented by low concentrations of adrenergic antagonists and apparently depend upon the presence in the molecules of a catechol moiety.

Original language	English
Pages (from-to)	1799-1803
Number of pages	5
Journal	Biochemical Pharmacology
Volume	30
Issue number	13
DOIs	https://doi.org/10.1016/0006-2952(81)90013-7
Publication status	Published - 1981

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title = "Effects of adrenergic agonists and antagonists and of the catechol nucleus on the Na+, K+-ATPase and Mg2+-ATPase activities of synaptosomes",

abstract = "The effects of adrenergic agonists, antagonists and other drugs on the Na+, K+-ATPase and Mg2+-ATPase activities of rat cerebral cortex synaptosomes have been determined. Noradrenaline, isoprenaline, dopamine, 1-DOPA and catechol stimulated the activities of the enzymes. The stimulatory effects were not prevented by low concentrations of adrenergic antagonists and apparently depend upon the presence in the molecules of a catechol moiety.",

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AU - Sawas, A H

AU - Gilbert, John C

PY - 1981

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N2 - The effects of adrenergic agonists, antagonists and other drugs on the Na+, K+-ATPase and Mg2+-ATPase activities of rat cerebral cortex synaptosomes have been determined. Noradrenaline, isoprenaline, dopamine, 1-DOPA and catechol stimulated the activities of the enzymes. The stimulatory effects were not prevented by low concentrations of adrenergic antagonists and apparently depend upon the presence in the molecules of a catechol moiety.

AB - The effects of adrenergic agonists, antagonists and other drugs on the Na+, K+-ATPase and Mg2+-ATPase activities of rat cerebral cortex synaptosomes have been determined. Noradrenaline, isoprenaline, dopamine, 1-DOPA and catechol stimulated the activities of the enzymes. The stimulatory effects were not prevented by low concentrations of adrenergic antagonists and apparently depend upon the presence in the molecules of a catechol moiety.

UR - https://www.scopus.com/pages/publications/0019429118

U2 - 10.1016/0006-2952(81)90013-7

DO - 10.1016/0006-2952(81)90013-7

M3 - Article

VL - 30

SP - 1799

EP - 1803

JO - Biochemical Pharmacology

JF - Biochemical Pharmacology

IS - 13

ER -

Effects of adrenergic agonists and antagonists and of the catechol nucleus on the Na⁺, K⁺-ATPase and Mg²⁺-ATPase activities of synaptosomes

Abstract

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