Effects of adrenergic agonists and antagonists and of the catechol nucleus on the Na+, K+-ATPase and Mg2+-ATPase activities of synaptosomes

A H Sawas, John C Gilbert

    Research output: Contribution to journalArticle

    Abstract

    The effects of adrenergic agonists, antagonists and other drugs on the Na+, K+-ATPase and Mg2+-ATPase activities of rat cerebral cortex synaptosomes have been determined. Noradrenaline, isoprenaline, dopamine, 1-DOPA and catechol stimulated the activities of the enzymes. The stimulatory effects were not prevented by low concentrations of adrenergic antagonists and apparently depend upon the presence in the molecules of a catechol moiety.

    Original languageEnglish
    Pages (from-to)1799-1803
    Number of pages5
    JournalBiochemical Pharmacology
    Volume30
    Issue number13
    DOIs
    Publication statusPublished - 1981

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