Abstract
Two terdentate NNO donor Schiff base ligands CH3C(OH){double bond, long}CHC(CH3){double bond, long}NCH2C5H4N [HL1] and C6H5C(OH){double bond, long}CHC(CH3){double bond, long}NCH2C5H4N [HL2] were used to synthesize two mononuclear square planar copper(II) complexes, [CuL1(CF3COO)] (1) and [CuL2(CF3COO)] (2). The complexes were characterized by elemental analyses, FT-IR, UV-vis spectral methods and their structures were established by single crystal X-ray diffraction study. The biochemical activity of the complexes towards DNA binding were performed using absorbance and fluorescence titration methods and their mode of binding with calf thymus DNA has been established by viscosity measurement technique. © 2010 Elsevier B.V. All rights reserved.
| Original language | English |
|---|---|
| Pages (from-to) | 265-273 |
| Number of pages | 9 |
| Journal | Journal of Molecular Structure |
| Volume | 975 |
| Issue number | 1-3 |
| DOIs | |
| Publication status | Published - 30 Jun 2010 |
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Keywords
- Bifurcated H-bonding
- Copper(II) complexes
- CT-DNA
- Hypochromism
- Intercalation
- Square planarity
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Effect of ligand substitution on DNA binding ability of two new square planar copper(II)-Schiff base complexes. / Sadhukhan, Dipali; Ray, Aurkie; Das, Saurabh; Rizzoli, Corrado; Rosair, Georgina M.; Mitra, Samiran.
In: Journal of Molecular Structure, Vol. 975, No. 1-3, 30.06.2010, p. 265-273.Research output: Contribution to journal › Article
TY - JOUR
T1 - Effect of ligand substitution on DNA binding ability of two new square planar copper(II)-Schiff base complexes
AU - Sadhukhan, Dipali
AU - Ray, Aurkie
AU - Das, Saurabh
AU - Rizzoli, Corrado
AU - Rosair, Georgina M.
AU - Mitra, Samiran
PY - 2010/6/30
Y1 - 2010/6/30
N2 - Two terdentate NNO donor Schiff base ligands CH3C(OH){double bond, long}CHC(CH3){double bond, long}NCH2C5H4N [HL1] and C6H5C(OH){double bond, long}CHC(CH3){double bond, long}NCH2C5H4N [HL2] were used to synthesize two mononuclear square planar copper(II) complexes, [CuL1(CF3COO)] (1) and [CuL2(CF3COO)] (2). The complexes were characterized by elemental analyses, FT-IR, UV-vis spectral methods and their structures were established by single crystal X-ray diffraction study. The biochemical activity of the complexes towards DNA binding were performed using absorbance and fluorescence titration methods and their mode of binding with calf thymus DNA has been established by viscosity measurement technique. © 2010 Elsevier B.V. All rights reserved.
AB - Two terdentate NNO donor Schiff base ligands CH3C(OH){double bond, long}CHC(CH3){double bond, long}NCH2C5H4N [HL1] and C6H5C(OH){double bond, long}CHC(CH3){double bond, long}NCH2C5H4N [HL2] were used to synthesize two mononuclear square planar copper(II) complexes, [CuL1(CF3COO)] (1) and [CuL2(CF3COO)] (2). The complexes were characterized by elemental analyses, FT-IR, UV-vis spectral methods and their structures were established by single crystal X-ray diffraction study. The biochemical activity of the complexes towards DNA binding were performed using absorbance and fluorescence titration methods and their mode of binding with calf thymus DNA has been established by viscosity measurement technique. © 2010 Elsevier B.V. All rights reserved.
KW - Bifurcated H-bonding
KW - Copper(II) complexes
KW - CT-DNA
KW - Hypochromism
KW - Intercalation
KW - Square planarity
UR - http://www.scopus.com/inward/record.url?scp=77953611841&partnerID=8YFLogxK
U2 - 10.1016/j.molstruc.2010.04.034
DO - 10.1016/j.molstruc.2010.04.034
M3 - Article
VL - 975
SP - 265
EP - 273
JO - Journal of Molecular Structure
JF - Journal of Molecular Structure
SN - 0022-2860
IS - 1-3
ER -