Early retinal blood vessel growth in normal and growth restricted rat pups raised in oxygen and room air

C A Dhaliwal, J Wade, T Gillespie, P Aspinall, N McIntosh, B W Fleck

Research output: Contribution to journalArticle

Abstract

Premature infants are born with incompletely vascularised retinas and are at a risk of developing retinopathy of prematurity (ROP). Rate of prenatal and postnatal body growth is important in the pathogenesis of ROP. The aim of this study was to develop a physiology-based rat model in order to study the effect of growth restriction and oxygen on early retinal vascular development.
Original languageEnglish
Pages (from-to)1592-6
Number of pages5
JournalBritish Journal of Ophthalmology
Volume95
Issue number11
DOIs
Publication statusPublished - 2011

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