Early retinal blood vessel growth in normal and growth restricted rat pups raised in oxygen and room air

C A Dhaliwal, J Wade, T Gillespie, P Aspinall, N McIntosh, B W Fleck

Research output: Contribution to journalArticle

Abstract

Premature infants are born with incompletely vascularised retinas and are at a risk of developing retinopathy of prematurity (ROP). Rate of prenatal and postnatal body growth is important in the pathogenesis of ROP. The aim of this study was to develop a physiology-based rat model in order to study the effect of growth restriction and oxygen on early retinal vascular development.
Original languageEnglish
Pages (from-to)1592-6
Number of pages5
JournalBritish Journal of Ophthalmology
Volume95
Issue number11
DOIs
Publication statusPublished - 2011

Fingerprint

Retinal Vessels
Retinopathy of Prematurity
Air
Oxygen
Growth
Premature Infants
Retina

Cite this

Dhaliwal, C A ; Wade, J ; Gillespie, T ; Aspinall, P ; McIntosh, N ; Fleck, B W. / Early retinal blood vessel growth in normal and growth restricted rat pups raised in oxygen and room air. In: British Journal of Ophthalmology. 2011 ; Vol. 95, No. 11. pp. 1592-6.
@article{168ceb4bf1854fdf9538f89ec2bec794,
title = "Early retinal blood vessel growth in normal and growth restricted rat pups raised in oxygen and room air",
abstract = "Premature infants are born with incompletely vascularised retinas and are at a risk of developing retinopathy of prematurity (ROP). Rate of prenatal and postnatal body growth is important in the pathogenesis of ROP. The aim of this study was to develop a physiology-based rat model in order to study the effect of growth restriction and oxygen on early retinal vascular development.",
author = "Dhaliwal, {C A} and J Wade and T Gillespie and P Aspinall and N McIntosh and Fleck, {B W}",
year = "2011",
doi = "10.1136/bjophthalmol-2011-300276",
language = "English",
volume = "95",
pages = "1592--6",
journal = "British Journal of Ophthalmology",
issn = "0007-1161",
publisher = "BMJ Publishing Group",
number = "11",

}

Early retinal blood vessel growth in normal and growth restricted rat pups raised in oxygen and room air. / Dhaliwal, C A; Wade, J; Gillespie, T; Aspinall, P; McIntosh, N; Fleck, B W.

In: British Journal of Ophthalmology, Vol. 95, No. 11, 2011, p. 1592-6.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Early retinal blood vessel growth in normal and growth restricted rat pups raised in oxygen and room air

AU - Dhaliwal, C A

AU - Wade, J

AU - Gillespie, T

AU - Aspinall, P

AU - McIntosh, N

AU - Fleck, B W

PY - 2011

Y1 - 2011

N2 - Premature infants are born with incompletely vascularised retinas and are at a risk of developing retinopathy of prematurity (ROP). Rate of prenatal and postnatal body growth is important in the pathogenesis of ROP. The aim of this study was to develop a physiology-based rat model in order to study the effect of growth restriction and oxygen on early retinal vascular development.

AB - Premature infants are born with incompletely vascularised retinas and are at a risk of developing retinopathy of prematurity (ROP). Rate of prenatal and postnatal body growth is important in the pathogenesis of ROP. The aim of this study was to develop a physiology-based rat model in order to study the effect of growth restriction and oxygen on early retinal vascular development.

U2 - 10.1136/bjophthalmol-2011-300276

DO - 10.1136/bjophthalmol-2011-300276

M3 - Article

VL - 95

SP - 1592

EP - 1596

JO - British Journal of Ophthalmology

JF - British Journal of Ophthalmology

SN - 0007-1161

IS - 11

ER -