Early retinal blood vessel growth in normal and growth restricted rat pups raised in oxygen and room air

C A Dhaliwal; J Wade; T Gillespie; P Aspinall; N McIntosh; B W Fleck

doi:10.1136/bjophthalmol-2011-300276

Early retinal blood vessel growth in normal and growth restricted rat pups raised in oxygen and room air

C A Dhaliwal, J Wade, T Gillespie, P Aspinall, N McIntosh, B W Fleck

Computer Science

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Abstract

Premature infants are born with incompletely vascularised retinas and are at a risk of developing retinopathy of prematurity (ROP). Rate of prenatal and postnatal body growth is important in the pathogenesis of ROP. The aim of this study was to develop a physiology-based rat model in order to study the effect of growth restriction and oxygen on early retinal vascular development.

Original language	English
Pages (from-to)	1592-6
Number of pages	5
Journal	British Journal of Ophthalmology
Volume	95
Issue number	11
DOIs	https://doi.org/10.1136/bjophthalmol-2011-300276
Publication status	Published - 2011

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10.1136/bjophthalmol-2011-300276

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title = "Early retinal blood vessel growth in normal and growth restricted rat pups raised in oxygen and room air",

abstract = "Premature infants are born with incompletely vascularised retinas and are at a risk of developing retinopathy of prematurity (ROP). Rate of prenatal and postnatal body growth is important in the pathogenesis of ROP. The aim of this study was to develop a physiology-based rat model in order to study the effect of growth restriction and oxygen on early retinal vascular development.",

author = "Dhaliwal, {C A} and J Wade and T Gillespie and P Aspinall and N McIntosh and Fleck, {B W}",

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AU - Wade, J

AU - Gillespie, T

AU - Aspinall, P

AU - McIntosh, N

AU - Fleck, B W

PY - 2011

Y1 - 2011

N2 - Premature infants are born with incompletely vascularised retinas and are at a risk of developing retinopathy of prematurity (ROP). Rate of prenatal and postnatal body growth is important in the pathogenesis of ROP. The aim of this study was to develop a physiology-based rat model in order to study the effect of growth restriction and oxygen on early retinal vascular development.

AB - Premature infants are born with incompletely vascularised retinas and are at a risk of developing retinopathy of prematurity (ROP). Rate of prenatal and postnatal body growth is important in the pathogenesis of ROP. The aim of this study was to develop a physiology-based rat model in order to study the effect of growth restriction and oxygen on early retinal vascular development.

U2 - 10.1136/bjophthalmol-2011-300276

DO - 10.1136/bjophthalmol-2011-300276

M3 - Article

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SN - 0007-1161

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SP - 1592

EP - 1596

JO - British Journal of Ophthalmology

JF - British Journal of Ophthalmology

IS - 11

ER -

Early retinal blood vessel growth in normal and growth restricted rat pups raised in oxygen and room air

Abstract

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