Dynamic Acoustic Field for Tuneable and Scalable Particle Sorting

G. D. Skotis, M.A.B. Andrade, S. Ritchie, D. R. S. Cumming, M. O. Riehle, Anne Bernassau

Research output: Contribution to conferencePaper

1 Citation (Scopus)
41 Downloads (Pure)

Abstract

Separation of cells is a critical process for studying cell properties, disease diagnostics, and therapeutics. Cell sorting by acoustic waves offers a means to separate cells on the basis of their size and physical properties in a label-free, contactless, and biocompatible manner. In this work, we introduce a unique technique, which use a dynamic acoustic field (DAF), based on the modulation of the phase of the standing wave. Using our dynamic acoustic field, we successfully separated 10 and 45 µm diameter polystyrene particles with a separation efficiency of 100%, and separated 6 and 10 µm polystyrene particles with an efficiency of ∼97%. We illustrate that DAF is capable of effectively separating dorsal root ganglion cells from heterogeneous medium. Finally, we demonstrate the scalability of the DAF method by sorting polystyrene particles of 5 mm and 2 mm diameter in air.
Original languageEnglish
Pages1-4
Number of pages4
DOIs
Publication statusPublished - 2015
EventIEEE International Ultrasonics Symposium 2015 - Taipei International Convention Center, Taipei, Taiwan, Province of China
Duration: 21 Oct 201524 Oct 2015

Conference

ConferenceIEEE International Ultrasonics Symposium 2015
Abbreviated titleIUS 2015
CountryTaiwan, Province of China
CityTaipei
Period21/10/1524/10/15

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