Dual purpose fibre – SERS pH sensing and bacterial analysis

Holly Fleming; Sarah McAughtrie; Bethany Mills; Michael G. Tanner; Angus Marks; Colin J. Campbell

doi:10.1039/C8AN01322E

Dual purpose fibre – SERS pH sensing and bacterial analysis

Holly Fleming, Sarah McAughtrie, Bethany Mills, Michael G. Tanner, Angus Marks, Colin J. Campbell

School of Engineering & Physical Sciences

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Abstract

The exploitation of fibre based Raman probes has been challenged by often complicated fabrication procedures and difficulties in reproducibility. Here, we have demonstrated a simple and cost-effective approach for sensing pH through an optical fibre, by employing a wax patterned filter paper-based substrate for surface enhanced Raman spectroscopy (SERS). Through this method, high reproducibility between fibres was achieved. In addition to sensing pH, it was possible to extract fluid samples containing P. aeruginosa for further analysis. This dual purpose fibre is bronchoscope deployable, and is able to gather information about both the host and pathogen, which may lead to an improved treatment plan in future in vivo applications.

Original language	English
Pages (from-to)	5918-5925
Number of pages	8
Journal	The Analyst
Volume	143
Issue number	24
Early online date	5 Oct 2018
DOIs	https://doi.org/10.1039/C8AN01322E
Publication status	Published - 21 Dec 2018

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Dual purpose fibre – SERS pH sensing and bacterial analysis

Abstract

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