Dual purpose fibre – SERS pH sensing and bacterial analysis

Holly Fleming, Sarah McAughtrie, Bethany Mills, Michael G. Tanner, Angus Marks, Colin J. Campbell

Research output: Contribution to journalArticle

Abstract

The exploitation of fibre based Raman probes has been challenged by often complicated fabrication procedures and difficulties in reproducibility. Here, we have demonstrated a simple and cost-effective approach for sensing pH through an optical fibre, by employing a wax patterned filter paper-based substrate for surface enhanced Raman spectroscopy (SERS). Through this method, high reproducibility between fibres was achieved. In addition to sensing pH, it was possible to extract fluid samples containing P. aeruginosa for further analysis. This dual purpose fibre is bronchoscope deployable, and is able to gather information about both the host and pathogen, which may lead to an improved treatment plan in future in vivo applications.
Original languageEnglish
Pages (from-to)5918-5925
Number of pages8
JournalThe Analyst
Volume143
Issue number24
Early online date5 Oct 2018
DOIs
Publication statusPublished - 21 Dec 2018

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Raman spectroscopy
Fibers
Waxes
Pathogens
Optical fibers
Fabrication
Fluids
Substrates
Costs

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Fleming, H., McAughtrie, S., Mills, B., Tanner, M. G., Marks, A., & Campbell, C. J. (2018). Dual purpose fibre – SERS pH sensing and bacterial analysis. The Analyst, 143(24), 5918-5925. https://doi.org/10.1039/C8AN01322E
Fleming, Holly ; McAughtrie, Sarah ; Mills, Bethany ; Tanner, Michael G. ; Marks, Angus ; Campbell, Colin J. / Dual purpose fibre – SERS pH sensing and bacterial analysis. In: The Analyst. 2018 ; Vol. 143, No. 24. pp. 5918-5925.
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Fleming, H, McAughtrie, S, Mills, B, Tanner, MG, Marks, A & Campbell, CJ 2018, 'Dual purpose fibre – SERS pH sensing and bacterial analysis', The Analyst, vol. 143, no. 24, pp. 5918-5925. https://doi.org/10.1039/C8AN01322E

Dual purpose fibre – SERS pH sensing and bacterial analysis. / Fleming, Holly; McAughtrie, Sarah; Mills, Bethany; Tanner, Michael G.; Marks, Angus; Campbell, Colin J.

In: The Analyst, Vol. 143, No. 24, 21.12.2018, p. 5918-5925.

Research output: Contribution to journalArticle

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Fleming H, McAughtrie S, Mills B, Tanner MG, Marks A, Campbell CJ. Dual purpose fibre – SERS pH sensing and bacterial analysis. The Analyst. 2018 Dec 21;143(24):5918-5925. https://doi.org/10.1039/C8AN01322E