Does everything now make (anti)sense?

J. A. Timmons, L. Good

    Research output: Contribution to journalArticle

    28 Citations (Scopus)

    Abstract

    The data generated by the FANTOM (Functional Annotation of Mouse) consortium, Compugen and Affymetrix have collectively provided evidence that most of the mammalian genomes are actively transcribed. The emergence of an antisense RNA world brings new practical complexities to the study and detection of gene expression. However, we also need to address the fundamental questions regarding the functional importance of these molecules. In this brief paper, we focus on non-coding natural antisense transcription, as it appears to be a potentially powerful mechanism for extending the complexity of the protein coding genome, which is currently unable to explain inter-species diversification. ©2006 Biochemical Society.

    Original languageEnglish
    Pages (from-to)1148-1150
    Number of pages3
    JournalBiochemical Society Transactions
    Volume34
    Issue number6
    DOIs
    Publication statusPublished - 2006

    Keywords

    • Biodiversity
    • Epigenetics
    • Imprinting
    • Natural antisense
    • Non-coding RNA
    • Transcription

    Fingerprint Dive into the research topics of 'Does everything now make (anti)sense?'. Together they form a unique fingerprint.

  • Cite this