Discovery of Novel Materials with Broad Resistance to Bacterial Attachment Using Combinatorial Polymer Microarrays

Andrew L. Hook, Chien-Yi Chang, Jing Yang, Steve Atkinson, Robert Langer, Daniel G. Anderson, Martyn C. Davies, Paul Williams, Morgan R. Alexander

    Research output: Contribution to journalArticle

    51 Citations (Scopus)

    Abstract

    A new class of bacteria-attachment-resistant materials is discovered using a multi-generation polymer microarray methodology that reduces bacterial attachment by up to 99.3% compared with a leading commercially available silver hydrogel anti-bacterial material. The coverage of three bacterial species, Pseudomonas aeruginosa, Staphylococcus aureus, and uropathogenic Escherichia coli is assessed.

    Original languageEnglish
    Pages (from-to)2542-2547
    Number of pages6
    JournalAdvanced Materials
    Volume25
    Issue number18
    DOIs
    Publication statusPublished - 14 May 2013

    Keywords

    • anti-fouling
    • bacteria
    • biofilms
    • high throughput
    • microarrays

    ASJC Scopus subject areas

    • Materials Science(all)
    • Mechanics of Materials
    • Mechanical Engineering

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