A mild and inexpensive method for direct hydrodecarboxylation of aliphatic carboxylic acids has been developed. The reaction does not require metals, light, or catalysts, rendering the protocol operationally simple, easy to scale, and more sustainable. Crucially, no additional H atom source is required in most cases, while a broad substrate scope and functional group tolerance are observed.
|Number of pages||6|
|Early online date||7 Jan 2022|
|Publication status||Published - 21 Jan 2022|
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry