Different Areas of Human Non-Primary Auditory Cortex Are Activated by Sounds with Spatial and Nonspatial Properties

In humans, neuroimaging studies have identified the planum temporale to be particularly responsive to both spatial and nonspatial attributes of sound. However, a functional segregation of the planum temporale along these acoustic dimensions has not been firmly established. We evaluated this scheme in a factorial design using modulated sounds that generated a percept of motion (spatial) or frequency modulation (nonspatial). In addition, these sounds were presented in the context of a motion detection and a frequency-modulation detection task to investigate the cortical effects of directing attention to different perceptual attributes of the sound. Motion produced stronger activation in the medial part of the planum temporale and frequency-modulation produced stronger activation in the lateral part of the planum temporale, as well as an additional non-primary area lateral to Heschl's gyrus. These separate subregions are consistent with the notion of divergent processing streams for spatial and nonspatial auditory information. Activation in the superior parietal cortex, putatively involved in the spatial pathway, was dependent on the task of motion detection and not simply on the presence of acoustic cues for motion. This finding suggests that the listening task is an important determinant of how the processing stream is engaged.