Diauxic growth of Clostridium thermosaccharolyticum on glucose and xylose

Joseph Aduse-Opoku, Wilfrid J. Mitchell

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    22 Citations (Scopus)


    Clostridium thermosaccharolyticum growing on medium containing glucose and xylose exhibits classical diauxic growth in which glucose is utilized during the first phase. The lag period between growth phases is associated with induction of synthesis of a xylose transport system together with the enzymes xylose isomerase and xylukokinase. Xylose metabolism by this organism is therefore shown to be inducible and subject to repression by glucose. Xylose utilization by cells adapted to this carbon source is also prevented immediately upon addition of glucose to the culture, suggesting a direct inhibitory effect of glucose on xylose uptake or metabolism. © 1988.

    Original languageEnglish
    Pages (from-to)45-49
    Number of pages5
    JournalFEMS Microbiology Letters
    Issue number1
    Publication statusPublished - Apr 1988


    • Clostridium thermosaccharolyticum
    • Diauxic growth
    • Regulation
    • Xylose metabolism


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