Design and experimental testing of an electro-thermal microgripper for cell manipulation

Aurelio Somà, Sonia Iamoni, Rodica Cristina Voicu, Raluca Muller, Muaiyd H. M. Al-Zandi, Changhai Wang

Research output: Contribution to journalArticle

Abstract

This paper presents the design, fabrication and experimental characterization of an electro-thermally actuated microgripper suitable for single-cell manipulation. The analysis of the mechanical properties of cells is of great interest both in medicine and biology because the study of the cellular mechanical behaviour and resistance is necessary in these fields. Microgrippers (Bio-MEMS) have an important role in the manipulation of biological tissues and cells. In recent works, the research group simulated the mechanical behavior of grippers and the different actuation strategies. Considering the dimensional specifications and targets imposed by actuation and biocompatibility, in this paper, a microgripper based on electro-thermal actuation is studied. Starting from previous numerical results, a novel SU8 structure is designed and realized according to the micro-fabrication constraints and then the structure is simulated using the finite element method (FEM)-based thermo-structural simulations in ANSYS. Therefore, the fabrication method and steps are presented and the gripper has been developed and tested. Finally, the tip displacements of the gripper, electro-thermally actuated in different operating conditions, are compared with those obtained by means of numerical FEM simulations. A good agreement is obtained between simulations and experimental results.

Original languageEnglish
Pages (from-to)1053–1060
Number of pages8
JournalMicrosystem Technologies
Volume24
Issue number2
Early online date5 Jun 2017
DOIs
Publication statusPublished - Feb 2018

Fingerprint

Grippers
actuation
manipulators
fabrication
finite element method
Testing
cells
Finite element method
Fabrication
simulation
Microfabrication
biocompatibility
Biocompatibility
biology
medicine
Medicine
microelectromechanical systems
MEMS
specifications
mechanical properties

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Hardware and Architecture
  • Electrical and Electronic Engineering

Cite this

Somà, Aurelio ; Iamoni, Sonia ; Voicu, Rodica Cristina ; Muller, Raluca ; Al-Zandi, Muaiyd H. M. ; Wang, Changhai. / Design and experimental testing of an electro-thermal microgripper for cell manipulation. In: Microsystem Technologies. 2018 ; Vol. 24, No. 2. pp. 1053–1060.
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abstract = "This paper presents the design, fabrication and experimental characterization of an electro-thermally actuated microgripper suitable for single-cell manipulation. The analysis of the mechanical properties of cells is of great interest both in medicine and biology because the study of the cellular mechanical behaviour and resistance is necessary in these fields. Microgrippers (Bio-MEMS) have an important role in the manipulation of biological tissues and cells. In recent works, the research group simulated the mechanical behavior of grippers and the different actuation strategies. Considering the dimensional specifications and targets imposed by actuation and biocompatibility, in this paper, a microgripper based on electro-thermal actuation is studied. Starting from previous numerical results, a novel SU8 structure is designed and realized according to the micro-fabrication constraints and then the structure is simulated using the finite element method (FEM)-based thermo-structural simulations in ANSYS. Therefore, the fabrication method and steps are presented and the gripper has been developed and tested. Finally, the tip displacements of the gripper, electro-thermally actuated in different operating conditions, are compared with those obtained by means of numerical FEM simulations. A good agreement is obtained between simulations and experimental results.",
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Design and experimental testing of an electro-thermal microgripper for cell manipulation. / Somà, Aurelio; Iamoni, Sonia; Voicu, Rodica Cristina; Muller, Raluca; Al-Zandi, Muaiyd H. M.; Wang, Changhai.

In: Microsystem Technologies, Vol. 24, No. 2, 02.2018, p. 1053–1060.

Research output: Contribution to journalArticle

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