Deactivation of gold(I) catalysts in the presence of thiols and amines – characterisation and catalysis

Paul C Young, Samantha L J Green, Georgina Margaret Rosair, Ai-Lan Lee*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

36 Citations (Scopus)
252 Downloads (Pure)

Abstract

Thiols and amines, which are common heteroatom nucleophiles in gold-catalysed reactions, are known to dampen the reactivity of gold catalysts. In this article, the identity and activity of gold(I) catalysts in the presence of thiols and amines is investigated. In the presence of thioacid, thiophenol and thiol, digold with bridging thiolate complexes [{Au( L)}(2)(mu-SR)][SbF6] are formed and have been fully characterised by NMR and X-ray crystallography. In the presence of amines and anilines, complexes [LAu-NH2R][SbF6] are formed instead. All new isolated gold complexes were investigated for their catalytic activity in order to compare the level of deactivation in each species.

Original languageEnglish
Pages (from-to)9645-9653
Number of pages9
JournalDalton Transactions
Volume42
Issue number26
Early online date9 May 2013
DOIs
Publication statusPublished - 9 May 2013

Keywords

  • DYNAMIC SOLUTION BEHAVIOR
  • RAY CRYSTAL-STRUCTURES
  • PI-ALKENE COMPLEXES
  • S BOND FORMATION
  • N-DONOR LIGANDS
  • GOLD(I)-CATALYZED CYCLOISOMERIZATION
  • 3,3-DISUBSTITUTED CYCLOPROPENES
  • CARBOPHILIC ACTIVATION
  • ALPHA-THIOALLENES
  • ORGANIC-REACTIONS

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