Conversion of 6α-alkoxyformamidopenicillanates into 6α-aminopenicillanates, and the formation of 6-spiropenicillanates

David H Bremner; Malcolm M Campbell; Graham Johnson

doi:10.1039/C39760000293

Conversion of 6α-alkoxyformamidopenicillanates into 6α-aminopenicillanates, and the formation of 6-spiropenicillanates

David H Bremner, Malcolm M Campbell, Graham Johnson

School of Engineering & Physical Sciences

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Methyl 6ß-phenoxyacetamido-6a- trichloroethoxyformamidopenicillanate has been converted into a 6a-aminopenicillanate; 6a-ethoxyformamido-6ß- phenoxyacetamidopenicillanates reacted with phosgene and base to afford unique (1-ethoxycarbonyl-3-phenoxyacetyl-2-oxo-1,3-diazetidine)-4-spiro-6'- penicillanates.

Original language	English
Pages (from-to)	293-294
Number of pages	2
Journal	Journal of the Chemical Society, Chemical Communications
Issue number	8
DOIs	https://doi.org/10.1039/C39760000293
Publication status	Published - 1976

Access to Document

10.1039/C39760000293

Cite this

@article{b4d1ea5d28954bb7b65cfda559255469,

title = "Conversion of 6α-alkoxyformamidopenicillanates into 6α-aminopenicillanates, and the formation of 6-spiropenicillanates",

abstract = "Methyl 6{\ss}-phenoxyacetamido-6a- trichloroethoxyformamidopenicillanate has been converted into a 6a-aminopenicillanate; 6a-ethoxyformamido-6{\ss}- phenoxyacetamidopenicillanates reacted with phosgene and base to afford unique (1-ethoxycarbonyl-3-phenoxyacetyl-2-oxo-1,3-diazetidine)-4-spiro-6'- penicillanates.",

author = "Bremner, {David H} and Campbell, {Malcolm M} and Graham Johnson",

year = "1976",

doi = "10.1039/C39760000293",

language = "English",

pages = "293--294",

journal = "Journal of the Chemical Society, Chemical Communications",

issn = "0022-4936",

publisher = "Chemical Society",

number = "8",

}

TY - JOUR

T1 - Conversion of 6α-alkoxyformamidopenicillanates into 6α-aminopenicillanates, and the formation of 6-spiropenicillanates

AU - Bremner, David H

AU - Campbell, Malcolm M

AU - Johnson, Graham

PY - 1976

Y1 - 1976

N2 - Methyl 6ß-phenoxyacetamido-6a- trichloroethoxyformamidopenicillanate has been converted into a 6a-aminopenicillanate; 6a-ethoxyformamido-6ß- phenoxyacetamidopenicillanates reacted with phosgene and base to afford unique (1-ethoxycarbonyl-3-phenoxyacetyl-2-oxo-1,3-diazetidine)-4-spiro-6'- penicillanates.

AB - Methyl 6ß-phenoxyacetamido-6a- trichloroethoxyformamidopenicillanate has been converted into a 6a-aminopenicillanate; 6a-ethoxyformamido-6ß- phenoxyacetamidopenicillanates reacted with phosgene and base to afford unique (1-ethoxycarbonyl-3-phenoxyacetyl-2-oxo-1,3-diazetidine)-4-spiro-6'- penicillanates.

U2 - 10.1039/C39760000293

DO - 10.1039/C39760000293

M3 - Article

SN - 0022-4936

SP - 293

EP - 294

JO - Journal of the Chemical Society, Chemical Communications

JF - Journal of the Chemical Society, Chemical Communications

IS - 8

ER -

Conversion of 6α-alkoxyformamidopenicillanates into 6α-aminopenicillanates, and the formation of 6-spiropenicillanates

Abstract

Access to Document

Fingerprint

Cite this