Conversion of 6α-alkoxyformamidopenicillanates into 6α-aminopenicillanates, and the formation of 6-spiropenicillanates

David H Bremner, Malcolm M Campbell, Graham Johnson

Research output: Contribution to journalArticle

Abstract

Methyl 6ß-phenoxyacetamido-6a- trichloroethoxyformamidopenicillanate has been converted into a 6a-aminopenicillanate; 6a-ethoxyformamido-6ß- phenoxyacetamidopenicillanates reacted with phosgene and base to afford unique (1-ethoxycarbonyl-3-phenoxyacetyl-2-oxo-1,3-diazetidine)-4-spiro-6'- penicillanates.

Original languageEnglish
Pages (from-to)293-294
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number8
DOIs
Publication statusPublished - 1976

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