Abstract
Duplication of the Escherichia coli bacterial cell culminates in the formation of a division septum that splits the progenitor cell into two identical daughter cells. Invagination of the cell envelope is brought about by the co-ordinated interplay of a family of septation-specific proteins that act locally at mid-cell at a specific time in the cell cycle. The majority of the genes known to be required for septum formation are found within the large mra cluster located at 2 min on the E. coli genetic map (nucleotides 89 552-107 474). Examination of the controls exerted on the mra operon shows that E. coli uses an extraordinary range of strategies to co-ordinate the expression of the cell division genes with respect to each other and to the cell cycle. Copyright (C) 2000 Federation of European Microbiological Societies.
Original language | English |
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Pages (from-to) | 1-7 |
Number of pages | 7 |
Journal | FEMS Microbiology Letters |
Volume | 187 |
Issue number | 1 |
DOIs | |
Publication status | Published - 1 Jun 2000 |
Keywords
- Cell division
- Escherichia coli
- Fts protein
- Gene expression
- Regulation
- Transcriptional organization