Continuous Hydrogenation of Alkynol in a Continuous Oscillatory Baffled Reactor

Francisca Navarro-Fuentes, Mark Andrew Keane, Xiong Wei Ni

Research output: Contribution to journalArticlepeer-review

Abstract

In this paper, we report, for the first time, that a multiphase catalytic hydrogenation of 3-butyn-2-ol over Pd/Al2O3 catalyst has successfully been running in a continuous oscillatory baffled reactor (COBR) for over 12 h. Catalyst stability and attrition were examined, the results show that there was no catalyst loss for the whole duration of operation, the catalyst was stable for 9 h with 97% selectivity at a target conversion of 95%. Catalyst deactivation thereafter was assessed at a rate of 0.03% per h, this means that it would take 17 days (or 2040 cycles) of operation to achieve 50% of the target conversion. This is significantly better than the corresponding batch operation where half catalyst activity was reached after 32 cycles. In addition, one of the advantages of using COBR is that it allows the screening of several operational parameters in a single reaction run, as the steady state of operation was readily attained within 1 to 1.5 residence times.

Original languageEnglish
JournalOrganic Process Research and Development
Early online date14 Jan 2021
DOIs
Publication statusE-pub ahead of print - 14 Jan 2021

Keywords

  • catalyst deactivation
  • continuous hydrogenation
  • continuous oscillatory baffled reactor
  • reaction rate
  • selectivity

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry

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