Compounds and their use as PDE4 activators

Julla Mary Adam; David Roger Adams

Compounds and their use as PDE4 activators

Julla Mary Adam (Inventor)
, David Roger Adams (Inventor)

Research output: Patent

94 Downloads (Pure)

Abstract

Compounds of Formula (I), which are activators of long form cyclic nucleotide phosphodiesterase-4 (PDE4) enzymes (isoforms) are provided. Methods and uses of these compounds for the treatment or prevention of disorders requiring a reduction of second messenger responses mediated by cyclic 3', 5'-adenosine monophosphate (cAMP) are also described. (Formula (I))

Original language	English
Patent number	WO2018060704(A1)
IPC	A61K31/4196,A61P1/00,A61P11/00,A61P13/00,A61P35/00,A61P5/00,A61P9/00,C07D249/08,C07D403/12
Priority date	28/09/16
Publication status	Published - 5 Apr 2018

ASJC Scopus subject areas

General Biochemistry,Genetics and Molecular Biology
Organic Chemistry

Access to Document

Download pdfFinal published version, 5.07 MB

Cite this

@misc{9b6f73579d4944e7bc39c799575b909b,

title = "Compounds and their use as PDE4 activators",

abstract = "Compounds of Formula (I), which are activators of long form cyclic nucleotide phosphodiesterase-4 (PDE4) enzymes (isoforms) are provided. Methods and uses of these compounds for the treatment or prevention of disorders requiring a reduction of second messenger responses mediated by cyclic 3', 5'-adenosine monophosphate (cAMP) are also described. (Formula (I))",

author = "Adam, \{Julla Mary\} and Adams, \{David Roger\}",

year = "2018",

month = apr,

day = "5",

language = "English",

publisher = "World Intellectual Property Organization (WIPO)",

type = "Patent",

note = "WO2018060704(A1); A61K31/4196,A61P1/00,A61P11/00,A61P13/00,A61P35/00,A61P5/00,A61P9/00,C07D249/08,C07D403/12",

}

TY - PAT

T1 - Compounds and their use as PDE4 activators

AU - Adam, Julla Mary

AU - Adams, David Roger

PY - 2018/4/5

Y1 - 2018/4/5

N2 - Compounds of Formula (I), which are activators of long form cyclic nucleotide phosphodiesterase-4 (PDE4) enzymes (isoforms) are provided. Methods and uses of these compounds for the treatment or prevention of disorders requiring a reduction of second messenger responses mediated by cyclic 3', 5'-adenosine monophosphate (cAMP) are also described. (Formula (I))

AB - Compounds of Formula (I), which are activators of long form cyclic nucleotide phosphodiesterase-4 (PDE4) enzymes (isoforms) are provided. Methods and uses of these compounds for the treatment or prevention of disorders requiring a reduction of second messenger responses mediated by cyclic 3', 5'-adenosine monophosphate (cAMP) are also described. (Formula (I))

M3 - Patent

M1 - WO2018060704(A1)

PB - World Intellectual Property Organization (WIPO)

ER -

Compounds and their use as PDE4 activators

Abstract

ASJC Scopus subject areas

Access to Document

Fingerprint

Cite this