Compounds and their use as PDE4 activators

Julla Mary Adam (Inventor), David Roger Adams (Inventor)

Research output: Patent

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Abstract

Compounds of Formula (I), which are activators of long form cyclic nucleotide phosphodiesterase-4 (PDE4) enzymes (isoforms) are provided. Methods and uses of these compounds for the treatment or prevention of disorders requiring a reduction of second messenger responses mediated by cyclic 3', 5'-adenosine monophosphate (cAMP) are also described. (Formula (I))
Original languageEnglish
Patent numberWO2018060704(A1)
IPCA61K31/4196,A61P1/00,A61P11/00,A61P13/00,A61P35/00,A61P5/00,A61P9/00,C07D249/08,C07D403/12
Priority date28/09/16
Publication statusPublished - 5 Apr 2018

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ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Organic Chemistry

Cite this

Adam, J. M., & Adams, D. R. (2018). IPC No. A61K31/4196, A61P1/00, A61P11/00, A61P13/00, A61P35/00, A61P5/00, A61P9/00, C07D249/08, C07D403/12. Compounds and their use as PDE4 activators. (Patent No. WO2018060704(A1)). World Intellectual Property Organization (WIPO).