Compounds and their use as PDE4 activators

Julla Mary Adam (Inventor), David Roger Adams (Inventor)

Research output: Patent

42 Downloads (Pure)


Compounds of Formula (I), which are activators of long form cyclic nucleotide phosphodiesterase-4 (PDE4) enzymes (isoforms) are provided. Methods and uses of these compounds for the treatment or prevention of disorders requiring a reduction of second messenger responses mediated by cyclic 3', 5'-adenosine monophosphate (cAMP) are also described. (Formula (I))
Original languageEnglish
Patent numberWO2018060704(A1)
Priority date28/09/16
Publication statusPublished - 5 Apr 2018

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Organic Chemistry


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