Compounds and their use as PDE4 activators

Julla Mary Adam (Inventor), David Roger Adams (Inventor)

Research output: Patent

Abstract

Compounds of Formula (I), which are activators of long form cyclic nucleotide phosphodiesterase-4 (PDE4) enzymes (isoforms) are provided. Methods and uses of these compounds for the treatment or prevention of disorders requiring a reduction of second messenger responses mediated by cyclic 3', 5'-adenosine monophosphate (cAMP) are also described. (Formula (I))
Original languageEnglish
Patent numberWO2018060704(A1)
IPCA61K31/4196,A61P1/00,A61P11/00,A61P13/00,A61P35/00,A61P5/00,A61P9/00,C07D249/08,C07D403/12
Priority date28/09/16
Publication statusPublished - 5 Apr 2018

Fingerprint

Type 4 Cyclic Nucleotide Phosphodiesterase
Cyclic Nucleotides
Second Messenger Systems
Cyclic AMP
Protein Isoforms
Enzymes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Organic Chemistry

Cite this

Adam, J. M., & Adams, D. R. (2018). IPC No. A61K31/4196, A61P1/00, A61P11/00, A61P13/00, A61P35/00, A61P5/00, A61P9/00, C07D249/08, C07D403/12. Compounds and their use as PDE4 activators. (Patent No. WO2018060704(A1)). World Intellectual Property Organization (WIPO).
Adam, Julla Mary (Inventor) ; Adams, David Roger (Inventor). / Compounds and their use as PDE4 activators. World Intellectual Property Organization (WIPO). IPC No.: A61K31/4196, A61P1/00, A61P11/00, A61P13/00, A61P35/00, A61P5/00, A61P9/00, C07D249/08, C07D403/12. Patent No.: WO2018060704(A1).
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abstract = "Compounds of Formula (I), which are activators of long form cyclic nucleotide phosphodiesterase-4 (PDE4) enzymes (isoforms) are provided. Methods and uses of these compounds for the treatment or prevention of disorders requiring a reduction of second messenger responses mediated by cyclic 3', 5'-adenosine monophosphate (cAMP) are also described. (Formula (I))",
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note = "WO2018060704(A1); A61K31/4196,A61P1/00,A61P11/00,A61P13/00,A61P35/00,A61P5/00,A61P9/00,C07D249/08,C07D403/12",

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Adam, JM & Adams, DR 2018, Compounds and their use as PDE4 activators, Patent No. WO2018060704(A1), IPC No. A61K31/4196, A61P1/00, A61P11/00, A61P13/00, A61P35/00, A61P5/00, A61P9/00, C07D249/08, C07D403/12.

Compounds and their use as PDE4 activators. / Adam, Julla Mary (Inventor); Adams, David Roger (Inventor).

World Intellectual Property Organization (WIPO). IPC No.: A61K31/4196, A61P1/00, A61P11/00, A61P13/00, A61P35/00, A61P5/00, A61P9/00, C07D249/08, C07D403/12. Patent No.: WO2018060704(A1).

Research output: Patent

TY - PAT

T1 - Compounds and their use as PDE4 activators

AU - Adam, Julla Mary

AU - Adams, David Roger

PY - 2018/4/5

Y1 - 2018/4/5

N2 - Compounds of Formula (I), which are activators of long form cyclic nucleotide phosphodiesterase-4 (PDE4) enzymes (isoforms) are provided. Methods and uses of these compounds for the treatment or prevention of disorders requiring a reduction of second messenger responses mediated by cyclic 3', 5'-adenosine monophosphate (cAMP) are also described. (Formula (I))

AB - Compounds of Formula (I), which are activators of long form cyclic nucleotide phosphodiesterase-4 (PDE4) enzymes (isoforms) are provided. Methods and uses of these compounds for the treatment or prevention of disorders requiring a reduction of second messenger responses mediated by cyclic 3', 5'-adenosine monophosphate (cAMP) are also described. (Formula (I))

M3 - Patent

M1 - WO2018060704(A1)

PB - World Intellectual Property Organization (WIPO)

ER -

Adam JM, Adams DR, inventors. Compounds and their use as PDE4 activators. A61K31/4196, A61P1/00, A61P11/00, A61P13/00, A61P35/00, A61P5/00, A61P9/00, C07D249/08, C07D403/12. 2018 Apr 5.