Chemically modifying peptides

Steven Cobb; Christopher Coxon; Graham Sandford

Chemically modifying peptides

Steven Cobb (Inventor), Christopher Coxon (Inventor), Graham Sandford (Inventor)

Research output: Patent

Abstract

A method for chemically modifying a peptide, derivative or analogue thereof is described. The method comprises contacting a peptide, derivative or analogue thereof with a fluoro-heteroaromatic compound to activate the peptide, derivative or analogue thereof. The activated peptide, derivative or analogue thereof is then contacted with a nucleophile or base to create a chemically modified peptide, derivative or analogue thereof.

Original language	English
Patent number	WO 2015/181544 A2
IPC	C07K 1/113 (2006.01)
Priority date	29/05/14
Filing date	28/05/15
Publication status	Published - 3 Dec 2015

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title = "Chemically modifying peptides",

abstract = "A method for chemically modifying a peptide, derivative or analogue thereof is described. The method comprises contacting a peptide, derivative or analogue thereof with a fluoro-heteroaromatic compound to activate the peptide, derivative or analogue thereof. The activated peptide, derivative or analogue thereof is then contacted with a nucleophile or base to create a chemically modified peptide, derivative or analogue thereof.",

author = "Steven Cobb and Christopher Coxon and Graham Sandford",

year = "2015",

month = dec,

day = "3",

language = "English",

publisher = "World Intellectual Property Organization",

type = "Patent",

note = "WO 2015/181544 A2; C07K 1/113 (2006.01)",

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TY - PAT

T1 - Chemically modifying peptides

AU - Cobb, Steven

AU - Coxon, Christopher

AU - Sandford, Graham

PY - 2015/12/3

Y1 - 2015/12/3

N2 - A method for chemically modifying a peptide, derivative or analogue thereof is described. The method comprises contacting a peptide, derivative or analogue thereof with a fluoro-heteroaromatic compound to activate the peptide, derivative or analogue thereof. The activated peptide, derivative or analogue thereof is then contacted with a nucleophile or base to create a chemically modified peptide, derivative or analogue thereof.

AB - A method for chemically modifying a peptide, derivative or analogue thereof is described. The method comprises contacting a peptide, derivative or analogue thereof with a fluoro-heteroaromatic compound to activate the peptide, derivative or analogue thereof. The activated peptide, derivative or analogue thereof is then contacted with a nucleophile or base to create a chemically modified peptide, derivative or analogue thereof.

M3 - Patent

M1 - WO 2015/181544 A2

Y2 - 2015/05/28

PB - World Intellectual Property Organization

ER -

Chemically modifying peptides

Abstract

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