Chemically modifying peptides

Steven Cobb (Inventor), Christopher Coxon (Inventor), Graham Sandford (Inventor)

Research output: Patent

Abstract

A method for chemically modifying a peptide, derivative or analogue thereof is described. The method comprises contacting a peptide, derivative or analogue thereof with a fluoro-heteroaromatic compound to activate the peptide, derivative or analogue thereof. The activated peptide, derivative or analogue thereof is then contacted with a nucleophile or base to create a chemically modified peptide, derivative or analogue thereof.
Original languageEnglish
Patent numberWO 2015/181544 A2
IPCC07K 1/113 (2006.01)
Priority date29/05/14
Filing date28/05/15
Publication statusPublished - 3 Dec 2015

Fingerprint Dive into the research topics of 'Chemically modifying peptides'. Together they form a unique fingerprint.

Cite this