Challenges in Modelling Biofluids in Microchannels

Xiangdong Xue; Mayur K. Patel; Chris Bailey; Maiwenn Kersaudy-Kerhoas; M. P Y Desmulliez

doi:10.1109/ESTC.2008.4684363

Challenges in Modelling Biofluids in Microchannels

Xiangdong Xue, Mayur K. Patel, Chris Bailey, Maiwenn Kersaudy-Kerhoas, M. P Y Desmulliez

School of Engineering & Physical Sciences

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Citation (Scopus)

Abstract

This paper presents the challenges encountered in modelling biofluids in microchannels. In particular blood separation implemented in a T-microchannel device is analysed. Microfluids behave different from the counterparts in the microscale and a different approach has been adopted here to model them, which emphasize the roles of viscous forces, high shear rate performance and particle interaction in microscope. A T-microchannel design is numerically analysed by means of computational fluid dynamics (CFD) to investigate the effectiveness of blood separation based on the bifurcation law and other bio-physical effects. The simulation shows that the device can separate blood cells from plasma. ©2008 IEEE.

Original language	English
Title of host publication	Proceedings - 2008 2nd Electronics Systemintegration Technology Conference, ESTC
Pages	287-292
Number of pages	6
DOIs	https://doi.org/10.1109/ESTC.2008.4684363
Publication status	Published - 2008
Event	2008 2nd Electronics Systemintegration Technology Conference - Greenwich, United Kingdom Duration: 1 Sept 2008 → 4 Sept 2008

Conference

Conference	2008 2nd Electronics Systemintegration Technology Conference
Abbreviated title	ESTC
Country/Territory	United Kingdom
City	Greenwich
Period	1/09/08 → 4/09/08

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10.1109/ESTC.2008.4684363

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@inproceedings{33b6558541d543e485fb2f48e6602542,

title = "Challenges in Modelling Biofluids in Microchannels",

abstract = "This paper presents the challenges encountered in modelling biofluids in microchannels. In particular blood separation implemented in a T-microchannel device is analysed. Microfluids behave different from the counterparts in the microscale and a different approach has been adopted here to model them, which emphasize the roles of viscous forces, high shear rate performance and particle interaction in microscope. A T-microchannel design is numerically analysed by means of computational fluid dynamics (CFD) to investigate the effectiveness of blood separation based on the bifurcation law and other bio-physical effects. The simulation shows that the device can separate blood cells from plasma. {\textcopyright}2008 IEEE.",

author = "Xiangdong Xue and Patel, {Mayur K.} and Chris Bailey and Maiwenn Kersaudy-Kerhoas and Desmulliez, {M. P Y}",

year = "2008",

doi = "10.1109/ESTC.2008.4684363",

language = "English",

isbn = "9781424428144",

pages = "287--292",

booktitle = "Proceedings - 2008 2nd Electronics Systemintegration Technology Conference, ESTC",

note = "2008 2nd Electronics Systemintegration Technology Conference, ESTC ; Conference date: 01-09-2008 Through 04-09-2008",

}

TY - GEN

T1 - Challenges in Modelling Biofluids in Microchannels

AU - Xue, Xiangdong

AU - Patel, Mayur K.

AU - Bailey, Chris

AU - Kersaudy-Kerhoas, Maiwenn

AU - Desmulliez, M. P Y

PY - 2008

Y1 - 2008

N2 - This paper presents the challenges encountered in modelling biofluids in microchannels. In particular blood separation implemented in a T-microchannel device is analysed. Microfluids behave different from the counterparts in the microscale and a different approach has been adopted here to model them, which emphasize the roles of viscous forces, high shear rate performance and particle interaction in microscope. A T-microchannel design is numerically analysed by means of computational fluid dynamics (CFD) to investigate the effectiveness of blood separation based on the bifurcation law and other bio-physical effects. The simulation shows that the device can separate blood cells from plasma. ©2008 IEEE.

AB - This paper presents the challenges encountered in modelling biofluids in microchannels. In particular blood separation implemented in a T-microchannel device is analysed. Microfluids behave different from the counterparts in the microscale and a different approach has been adopted here to model them, which emphasize the roles of viscous forces, high shear rate performance and particle interaction in microscope. A T-microchannel design is numerically analysed by means of computational fluid dynamics (CFD) to investigate the effectiveness of blood separation based on the bifurcation law and other bio-physical effects. The simulation shows that the device can separate blood cells from plasma. ©2008 IEEE.

U2 - 10.1109/ESTC.2008.4684363

DO - 10.1109/ESTC.2008.4684363

M3 - Conference contribution

SN - 9781424428144

SP - 287

EP - 292

BT - Proceedings - 2008 2nd Electronics Systemintegration Technology Conference, ESTC

T2 - 2008 2nd Electronics Systemintegration Technology Conference

Y2 - 1 September 2008 through 4 September 2008

ER -

Challenges in Modelling Biofluids in Microchannels

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