Cephalosporin sulphoxides: Functionalization at C-2 and C-4

David H Bremner, Malcolm M Campbell

Research output: Contribution to journalArticle

Abstract

Deacetoxycephalosporanate (S)-1-oxide 2-anions afforded (a) the Michael adducts with acrylonitrile, (b) Pummerer reactions with alkoxychloroformates, and (c) diazo-exchange reactions with tosyl azide, whereas the (R)-oxide under similar conditions reacted only with acrylonitrile giving a Michael adduct at C-4.

Original languageEnglish
Pages (from-to)538-539
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number14
DOIs
Publication statusPublished - 1976

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