TY - JOUR
T1 - Cephalosporin sulphoxides
T2 - Functionalization at C-2 and C-4
AU - Bremner, David H
AU - Campbell, Malcolm M
PY - 1976
Y1 - 1976
N2 - Deacetoxycephalosporanate (S)-1-oxide 2-anions afforded (a) the Michael adducts with acrylonitrile, (b) Pummerer reactions with alkoxychloroformates, and (c) diazo-exchange reactions with tosyl azide, whereas the (R)-oxide under similar conditions reacted only with acrylonitrile giving a Michael adduct at C-4.
AB - Deacetoxycephalosporanate (S)-1-oxide 2-anions afforded (a) the Michael adducts with acrylonitrile, (b) Pummerer reactions with alkoxychloroformates, and (c) diazo-exchange reactions with tosyl azide, whereas the (R)-oxide under similar conditions reacted only with acrylonitrile giving a Michael adduct at C-4.
UR - http://www.scopus.com/inward/record.url?scp=37049102515&partnerID=8YFLogxK
U2 - 10.1039/C39760000538
DO - 10.1039/C39760000538
M3 - Article
SN - 0022-4936
SP - 538
EP - 539
JO - Journal of the Chemical Society, Chemical Communications
JF - Journal of the Chemical Society, Chemical Communications
IS - 14
ER -