Three, structurally characterised, bis-phen Cu(ii) complexes of the phthalate isomers display rapid, low micromolar in vitro cytotoxicity against a range of epithelial tumour cells. The complexes induce relaxation of supercoiled plasmid DNA in the absence of external reducing agents and display efficient CT-DNA, Poly[d(A-T)]2 and Poly[d(G-C)]2 binding. © 2011 The Royal Society of Chemistry.
|Number of pages||4|
|Publication status||Published - 7 Feb 2011|