Abstract
Three, structurally characterised, bis-phen Cu(ii) complexes of the phthalate isomers display rapid, low micromolar in vitro cytotoxicity against a range of epithelial tumour cells. The complexes induce relaxation of supercoiled plasmid DNA in the absence of external reducing agents and display efficient CT-DNA, Poly[d(A-T)]2 and Poly[d(G-C)]2 binding. © 2011 The Royal Society of Chemistry.
Original language | English |
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Pages (from-to) | 1024-1027 |
Number of pages | 4 |
Journal | Dalton Transactions |
Volume | 40 |
Issue number | 5 |
DOIs | |
Publication status | Published - 7 Feb 2011 |