Biomechanical response of lumbar intervertebral disc in daily sitting postures: a poroelastic finite element analysis

Liang-Dong Zheng, Yu-Ting Cao, Yi-Ting Yang, Meng-Lei Xu, Hui-Zi Zeng, Shi-Jie Zhu, Antonio Candito, Yuhang Chen, Rui Zhu*, Li-Ming Cheng

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)
48 Downloads (Pure)


This study aims to establish and validate a poroelastic L4–L5 finite element model to evaluate the effect of different sitting postures and their durations on the mechanical responses of the disc. During the sustained loading conditions, the height loss, fluid loss and von-Mises stress gradually increased, but the intradiscal pressure decreased. The varying rates of aforementioned parameters were more significant at the initial loading stage and less so at the end. The predicted values in the flexed sitting posture were significantly greater than other postures. The extended sitting posture caused an obvious von-Mises stress concentration in the posterior region of the inter-lamellar matrix. From the biomechanical perspective, prolonged sitting may pose a high risk of lumbar disc degeneration, and therefore adjusting the posture properly in the early stage of sitting time may be useful to mitigate that. Additionally, upright sitting is a safer posture, while flexed sitting posture is more harmful.

Original languageEnglish
Pages (from-to)1941-1950
Number of pages10
JournalComputer Methods in Biomechanics and Biomedical Engineering
Issue number16
Early online date28 Dec 2022
Publication statusPublished - 10 Dec 2023


  • daily sitting postures
  • finite element analysis
  • Lumbar intervertebral disc
  • poroelastic model

ASJC Scopus subject areas

  • Bioengineering
  • Biomedical Engineering
  • Human-Computer Interaction
  • Computer Science Applications


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