Balamuthia mandrillaris resistance to hostile conditions

Ruqaiyyah Siddiqui; Antonio Ortega-Rivas; Naveed Ahmed Khan

doi:10.1099/jmm.0.47694-0

Balamuthia mandrillaris resistance to hostile conditions

Ruqaiyyah Siddiqui, Antonio Ortega-Rivas, Naveed Ahmed Khan

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

The resistance of Balamuthia mandrillaris to physical, chemical and radiological conditions was tested. Following treatments, viability was determined by culturing amoebae on human brain microvascular endothelial cells for up to 12 days. B. mandrillaris cysts were resistant to repeated freeze-thawing (five times), temperatures of up to 70 degrees C, 0.5 % SDS, 25 p.p.m. chlorine, 10 microg pentamidine isethionate ml(-1) and 200 mJ UV irradiation cm(-2).

Original language	English
Pages (from-to)	428-431
Number of pages	4
Journal	Journal of Medical Microbiology
Volume	57
Issue number	4
DOIs	https://doi.org/10.1099/jmm.0.47694-0
Publication status	Published - Apr 2008

Keywords

Animals
Brain/blood supply
Cells, Cultured
Chlorine/pharmacology
Endothelial Cells/parasitology
Endothelium, Vascular/cytology
Freezing
Heat-Shock Response
Hot Temperature
Humans
Lobosea/drug effects
Pentamidine/pharmacology
Sodium Dodecyl Sulfate/pharmacology
Trophozoites/drug effects
Ultraviolet Rays

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title = "Balamuthia mandrillaris resistance to hostile conditions",

abstract = "The resistance of Balamuthia mandrillaris to physical, chemical and radiological conditions was tested. Following treatments, viability was determined by culturing amoebae on human brain microvascular endothelial cells for up to 12 days. B. mandrillaris cysts were resistant to repeated freeze-thawing (five times), temperatures of up to 70 degrees C, 0.5 % SDS, 25 p.p.m. chlorine, 10 microg pentamidine isethionate ml(-1) and 200 mJ UV irradiation cm(-2).",

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author = "Ruqaiyyah Siddiqui and Antonio Ortega-Rivas and Khan, {Naveed Ahmed}",

year = "2008",

month = apr,

doi = "10.1099/jmm.0.47694-0",

language = "English",

volume = "57",

pages = "428--431",

journal = "Journal of Medical Microbiology",

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publisher = "Society for General Microbiology",

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T1 - Balamuthia mandrillaris resistance to hostile conditions

AU - Siddiqui, Ruqaiyyah

AU - Ortega-Rivas, Antonio

AU - Khan, Naveed Ahmed

PY - 2008/4

Y1 - 2008/4

N2 - The resistance of Balamuthia mandrillaris to physical, chemical and radiological conditions was tested. Following treatments, viability was determined by culturing amoebae on human brain microvascular endothelial cells for up to 12 days. B. mandrillaris cysts were resistant to repeated freeze-thawing (five times), temperatures of up to 70 degrees C, 0.5 % SDS, 25 p.p.m. chlorine, 10 microg pentamidine isethionate ml(-1) and 200 mJ UV irradiation cm(-2).

AB - The resistance of Balamuthia mandrillaris to physical, chemical and radiological conditions was tested. Following treatments, viability was determined by culturing amoebae on human brain microvascular endothelial cells for up to 12 days. B. mandrillaris cysts were resistant to repeated freeze-thawing (five times), temperatures of up to 70 degrees C, 0.5 % SDS, 25 p.p.m. chlorine, 10 microg pentamidine isethionate ml(-1) and 200 mJ UV irradiation cm(-2).

KW - Animals

KW - Brain/blood supply

KW - Cells, Cultured

KW - Chlorine/pharmacology

KW - Endothelial Cells/parasitology

KW - Endothelium, Vascular/cytology

KW - Freezing

KW - Heat-Shock Response

KW - Hot Temperature

KW - Humans

KW - Lobosea/drug effects

KW - Pentamidine/pharmacology

KW - Sodium Dodecyl Sulfate/pharmacology

KW - Trophozoites/drug effects

KW - Ultraviolet Rays

U2 - 10.1099/jmm.0.47694-0

DO - 10.1099/jmm.0.47694-0

M3 - Article

C2 - 18349360

SN - 0022-2615

VL - 57

SP - 428

EP - 431

JO - Journal of Medical Microbiology

JF - Journal of Medical Microbiology

IS - 4

ER -

Balamuthia mandrillaris resistance to hostile conditions

Abstract

Keywords

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